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'''Meckel diverticulum''' (also '''Meckel's diverticulum'''), is congenital structure of the distal [[small bowel]] that occasionally gets inflamed and may present with appendicitis-like symptoms. | |||
==General== | |||
*Most common congenital anomaly of the gastrointestinal tract.<ref name=pmid15026601>{{Cite journal | last1 = Levy | first1 = AD. | last2 = Hobbs | first2 = CM. | title = From the archives of the AFIP. Meckel diverticulum: radiologic features with pathologic Correlation. | journal = Radiographics | volume = 24 | issue = 2 | pages = 565-87 | month = | year = | doi = 10.1148/rg.242035187 | PMID = 15026601 }}</ref> | |||
**Remnant of the ''omphalomesenteric duct'' - a connection of the yolk sac and midgut. | |||
The rule of 2s: | |||
*2 feet from the terminal ileum | |||
*2% of the population | |||
*2% symptomatic. | |||
*2 inches long. | |||
*2 year old. | |||
*2 types of epithelium - gastric and pancreatic. | |||
Main clinical DDx of a symptomatic Meckel diverticulum: | |||
*[[Appendicitis]]. | |||
==Gross== | |||
*Antimesenteric attachement, i.e. a ''Meckel's diverticulum'' hangs off the side opposite of the mesentery. | |||
Image: | |||
*[http://commons.wikimedia.org/wiki/File:Meckel%27s_Diverticulum_AFIP.jpg Meckel diverticulum - (AFIP/WC)]. | |||
==Microscopic== | |||
Features:<ref name=pmid15026601/> | |||
*Small bowel mucosa. | |||
*+/-Gastric mucosa: | |||
**Foveolar epithelium: champagne flute-like columnar epithelium. | |||
**Oxyntic mucosa: parietal cells (pink) and chief cells (purple). | |||
*+/-Pancreatic epithelium: | |||
**Pancreatic acini. | |||
===Images=== | |||
*[http://radiographics.rsna.org/content/24/2/565/F12.expansion.html Gastric foveolar epithelium in a MD (radiographics.rsna.org)]. | |||
*[http://radiographics.rsna.org/content/24/2/565/F15.expansion.html Gastric glands in a MD (radiographics.rsna.org)]. | |||
*[http://radiographics.rsna.org/content/24/2/565.long Pancreatic glands in a MD (radiographics.rsna.org)]. | |||
==See also== | |||
*[[Small intestine]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||