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Difference between revisions of "Testis"
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update the term ITGCN --> GCNIS
(→Other: +met) |
(update the term ITGCN --> GCNIS) |
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Image:Seminiferous_tubule_and_sperm_low_mag.jpg | Seminiferous tubule and sperm - low mag. (WC/Nephron) | Image:Seminiferous_tubule_and_sperm_low_mag.jpg | Seminiferous tubule and sperm - low mag. (WC/Nephron) | ||
Image:Seminiferous_tubule_and_sperm.jpg | Seminiferous tubule and sperm - high mag. (WC/Nephron) | Image:Seminiferous_tubule_and_sperm.jpg | Seminiferous tubule and sperm - high mag. (WC/Nephron) | ||
Image:Intratubular_germ_cell_neoplasia_-_2_-_very_high_mag.jpg | Benign seminiferous tubules and ITGCN. (WC/Nephron) | Image:Intratubular_germ_cell_neoplasia_-_2_-_very_high_mag.jpg | Benign seminiferous tubules and GCNIS (ITGCN). (WC/Nephron) | ||
</gallery> | </gallery> | ||
====Interstitial==== | ====Interstitial==== | ||
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! Image | ! Image | ||
|- | |- | ||
| [[ | | [[Germ cell neoplasia in situ]] (GCNIS) | ||
| nests of small fried egg cells | | nests of small fried egg cells | ||
| large central nucleus, clear <br>cytoplasm, round ''or'' polygonal nuclear membrane, [[nucleoli]]<ref name=Ref_GUP538>{{Ref GUP|538}}</ref> | | large central nucleus, clear <br>cytoplasm, round ''or'' polygonal nuclear membrane, [[nucleoli]]<ref name=Ref_GUP538>{{Ref GUP|538}}</ref> | ||
| CD117 | | CD117 | ||
| appearance similar to seminoma | | appearance similar to seminoma | ||
| [[Image:Intratubular_germ_cell_neoplasia_high_mag_cropped.jpg|thumb|center|150px| | | [[Image:Intratubular_germ_cell_neoplasia_high_mag_cropped.jpg|thumb|center|150px|GCNIS (WC)]] | ||
|- | |- | ||
| [[Seminoma]] | | [[Seminoma]] | ||
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| [[Image:Teratoma_2_low_mag.jpg|thumb|center|150px|Teratoma (WC)]] | | [[Image:Teratoma_2_low_mag.jpg|thumb|center|150px|Teratoma (WC)]] | ||
|- | |- | ||
| [[Spermatocytic | | [[Spermatocytic tumour]] (previously ''spermatocytic seminoma'') | ||
| population of 3 cells | | population of 3 cells | ||
| pop.: (1) small cell with high [[NC ratio]] (mature lymphocyte-like), (2) medium with nucleoli, (3) large cells with filamentous chromatin - few present | | pop.: (1) small cell with high [[NC ratio]] (mature lymphocyte-like), (2) medium with nucleoli, (3) large cells with filamentous chromatin - few present | ||
| ? | | ? | ||
| does not arise from | | does not arise from GCNIS, no lymphocytic infiltrate (like in seminoma) | ||
| [[Image:Spermatocytic_seminoma_high_mag.jpg|thumb|center|150px|Spermatocytic | | [[Image:Spermatocytic_seminoma_high_mag.jpg|thumb|center|150px|Spermatocytic tumour (WC)]] | ||
|- | |- | ||
| [[Mixed germ cell tumour]] | | [[Mixed germ cell tumour]] | ||
| Line 273: | Line 273: | ||
DDx: | DDx: | ||
*[[ | *[[GCNIS]] (ITGCN). | ||
*[[Seminoma]]. | *[[Seminoma]]. | ||
*Tertiary [[syphilis]] - classically, plasma cell rich.<ref name=pmid22343746>{{Cite journal | last1 = Sekita | first1 = N. | last2 = Nishikawa | first2 = R. | last3 = Fujimura | first3 = M. | last4 = Sugano | first4 = I. | last5 = Mikami | first5 = K. | title = [Syphilitic orchitis: a case report]. | journal = Hinyokika Kiyo | volume = 58 | issue = 1 | pages = 53-5 | month = Jan | year = 2012 | doi = | PMID = 22343746 }}</ref> | *Tertiary [[syphilis]] - classically, plasma cell rich.<ref name=pmid22343746>{{Cite journal | last1 = Sekita | first1 = N. | last2 = Nishikawa | first2 = R. | last3 = Fujimura | first3 = M. | last4 = Sugano | first4 = I. | last5 = Mikami | first5 = K. | title = [Syphilitic orchitis: a case report]. | journal = Hinyokika Kiyo | volume = 58 | issue = 1 | pages = 53-5 | month = Jan | year = 2012 | doi = | PMID = 22343746 }}</ref> | ||
| Line 302: | Line 302: | ||
=Premalignant= | =Premalignant= | ||
== | ==Germ cell neoplasia in situ== | ||
* | *Previously ''intratubular germ cell neoplasia'' (abbreviated ''ITGCN''). | ||
{{Main| | {{Main|Germ cell neoplasia in situ}} | ||
=Germ cell tumours= | =Germ cell tumours= | ||
| Line 311: | Line 311: | ||
{{Main|Seminoma}} | {{Main|Seminoma}} | ||
==Spermatocytic | ==Spermatocytic tumour== | ||
{{Main|Spermatocytic | *Previously ''spermatocytic seminoma''. | ||
{{Main|Spermatocytic tumour}} | |||
==Yolk sac tumour== | ==Yolk sac tumour== | ||