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Difference between revisions of "Leydig cell tumour"
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| Micro = cytoplasmic vacuolization, cytoplasm -- clear to eosinophilic, +/-''Reinke crystals'' (cylindrical crystalloid -- eosinophilic cytoplasmic bodies), +/-[[nucleoli]] common, round nuclei | | Micro = cytoplasmic vacuolization, cytoplasm -- clear to eosinophilic, +/-''Reinke crystals'' (cylindrical crystalloid -- eosinophilic cytoplasmic bodies), +/-[[nucleoli]] common, round nuclei | ||
| Subtypes = benign (common), malignant (rare) | | Subtypes = benign (common), malignant (rare) | ||
| LMDDx = [[spermatocytic | | LMDDx = [[spermatocytic tumour]] (testis only), [[pregnancy luteoma]] (females only), [[Sertoli-Leydig cell tumour]] | ||
| Stains = | | Stains = | ||
| IHC = inhibin-alpha +ve, calretinin +ve, melan A +ve | | IHC = inhibin-alpha +ve, calretinin +ve, melan A +ve | ||
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DDx: | DDx: | ||
*[[Spermatocytic | *[[Spermatocytic tumour]] (previously ''spermatocytic seminoma'') - may have eosinophilic cytoplasm. | ||
*[[Pregnancy luteoma]] - occurs during pregnancy, as the name implies. | *[[Pregnancy luteoma]] - occurs during pregnancy, as the name implies. | ||
*Leydig cell hyperplasia. | *Leydig cell hyperplasia. | ||