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(→Juvenile polyp vs. solitary rectal ulcer: new section) |
(→Tubular adenoma (colon) - negative of high-grade dysplasia: new section) |
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====Comment==== | ====Comment==== | ||
The histomorphologic features in this specimen are those of a benign, chronic process; however, they are not distinctive. They are compatible with (1) a juvenile polyp, (2) a polypoid solitary rectal ulcer, and (3) an inflammatory pseudopolyp. As an inflammatory pseudopolyp is in the pathologic differential diagnosis, inflammatory bowel disease should be considered clinically. | The histomorphologic features in this specimen are those of a benign, chronic process; however, they are not distinctive. They are compatible with (1) a juvenile polyp, (2) a polypoid solitary rectal ulcer, and (3) an inflammatory pseudopolyp. As an inflammatory pseudopolyp is in the pathologic differential diagnosis, inflammatory bowel disease should be considered clinically. | ||
== Tubular adenoma (colon) - negative of high-grade dysplasia == | |||
===Microscopic description=== | |||
The sections show normal colonic-type mucosa and abnormal mucosal glands that have, from crypt base to luminal aspect, nuclear pseudostratification/crowding, nuclear hyperchromasia and enlargement, goblet cell paucity, and cytoplasmic hyperchromasia. | |||
The abnormal nuclei main basal stratification. There is no definite cribriforming of glands, and no sheeting of the atypical epithelium. No lamina propria invasion is identified. Completeness of excision is best assessed endoscopically. | |||
===Final diagnosis=== | |||
Polyp, transverse colon, excision - tubular adenoma, negative for high-grade dysplasia. |
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