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Difference between revisions of "Chordoma"
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→IHC
(→IHC) |
(→IHC) |
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**CK7 -ve (1 +ve/16). | **CK7 -ve (1 +ve/16). | ||
**CK20 -ve (0 +ve/16). | **CK20 -ve (0 +ve/16). | ||
Classic chordoma panel:<ref name=pmid24296480>{{Cite journal | last1 = Shen | first1 = J. | last2 = Shi | first2 = Q. | last3 = Lu | first3 = J. | last4 = Wang | first4 = DL. | last5 = Zou | first5 = TM. | last6 = Yang | first6 = HL. | last7 = Zhu | first7 = GQ. | title = Histological study of chordoma origin from fetal notochordal cell rests. | journal = Spine (Phila Pa 1976) | volume = 38 | issue = 25 | pages = 2165-70 | month = Dec | year = 2013 | doi = 10.1097/BRS.0000000000000010 | PMID = 24296480 }}</ref> | |||
*EMA, AE1/AE3, CAM5.2, vimentin, S-100. | |||
Key points: | Key points: | ||
*Brachyury is not a commonly stocked antibody. | *Brachyury is not a commonly stocked antibody. | ||
*Chordoma will be S100 '''AND''' | *Chordoma will be S100 '''AND''' epithelial marker positive. | ||
*Many other items in the | *Many other items in the DDx will be either S100 '''OR''' epithelial marker positive. | ||
==See also== | ==See also== | ||