Difference between revisions of "Small round cell tumours"

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==Tabular comparison==
==Tabular comparison==
Adapted from Thorner:<ref>PST. 14 February 2011.</ref>
{| class="wikitable"
{| class="wikitable"
| '''Tumour'''
| '''Tumour'''
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|-
|-
| Hepatoblastoma
| Hepatoblastoma
|
| fetal hepatocytes (~ 1:3 NC ratio, eosinophilic cytoplasm)
| liver
| liver
| AFP
| AFP
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| Nephroblastoma (Wilms tumour)
| Nephroblastoma (Wilms tumour)
| triphasic - (1) blue cells (blastema), (2) spindle cells (stroma), (3) tubular structures (epithelial)
| triphasic - (1) blue cells (blastema), (2) spindle cells (stroma), (3) tubular structures (epithelial)
| kidney
| kidney lesion, various syndromes
| WT-1+
| WT-1+
|-
|-
| Retinoblastoma
| Retinoblastoma
|
| Flexner-Wintersteiner rosette (rosette with empty centre (donut hole))<ref name=pmid16551982>{{cite journal |author=Wippold FJ, Perry A |title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes |journal=AJNR Am J Neuroradiol |volume=27 |issue=3 |pages=488–92 |year=2006 |month=March |pmid=16551982 |doi= |url=}}</ref>
| eye
| eye lesion; +/-RB1 gene mutations (familial)
|
|
|-
|-
| Medulloblastoma
| Medulloblastoma
|
| Homer-Wright rosettes (rosette with a meshwork of fibers (neuropil) at the centre)<ref name=pmid16551982>{{cite journal |author=Wippold FJ, Perry A |title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes |journal=AJNR Am J Neuroradiol |volume=27 |issue=3 |pages=488–92 |year=2006 |month=March |pmid=16551982 |doi= |url=}}</ref>
|  
| +/-nevoid basal cell carcinoma syndrome
|
|
|-
|-
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