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Difference between revisions of "P63"
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→Pattern
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==Pattern== | ==Pattern== | ||
*Nuclear staining. | *Nuclear staining. | ||
*Stains basal cells in a normal squamous epithelium. | |||
**Superficial cells are typically negative. | |||
**In dysplasia, the staining is seen more superficially,<ref name=pmid19700941>{{Cite journal | last1 = Houghton | first1 = O. | last2 = McCluggage | first2 = WG. | title = The expression and diagnostic utility of p63 in the female genital tract. | journal = Adv Anat Pathol | volume = 16 | issue = 5 | pages = 316-21 | month = Sep | year = 2009 | doi = 10.1097/PAP.0b013e3181b507c6 | PMID = 19700941 }}</ref> as one might expect as most squamous carcinomas are positive for p63. | |||
Note: | Note: | ||