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| =Specific entities= | | =Specific entities= |
| ==Parathyroid hyperplasia== | | ==Parathyroid hyperplasia== |
| ===General===
| | {{Main|Parathyroid hyperplasia}} |
| *Chief cell hyperplasia - associated with MEN 1, MEN 2A.<ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970475-2 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970475-2]. Accessed on: 29 July 2010.</ref>
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| *Parathyroid hyperplasia - classically assoc. with renal failure.
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| ===Gross===
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| *Classically all parathyroid glands are involved; however, some may be spared making it difficult to differentiate this from parathyroid adenoma.<ref name=Ref_PBoD8_1128>{{Ref PBoD8|1128}}</ref>
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| ===Microscopic===
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| Features:<ref name=Ref_PBoD8_1128>{{Ref PBoD8|1128}}</ref>
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| *Classically have abundant adipose tissue.
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| *+/-Water-clear cells ("water-clear cell hyperplasia").
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| Note:
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| *Generally, it is impossible to discern between [[parathyroid adenoma]]s and [[parathyroid hyperplasia]]s by histology alone.<ref name=Ref_BITFS191>{{Ref BITFS|191}}</ref>
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| **One requires information of the size of the other glands to make the diagnosis.
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| DDx:
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| *[[Parathyroid adenoma]] - classically have a rim of normal parathyroid gland around it.
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| ===Sign out===
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| <pre>
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| A. Right Superior Parathyroid, Excision:
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| - Parathyroid tissue compatible with hyperplasia.
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| B. Right Inferior Parathyroid, Excision:
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| - Parathyroid tissue compatible with hyperplasia.
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| C. Portion of Left Inferior Parathyroid, Excision:
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| - Parathyroid tissue compatible with hyperplasia.
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| D. Left Superior Parathyroid, Excision:
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| - Parathyroid tissue compatible with hyperplasia.
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| </pre>
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| ==Parathyroid adenoma== | | ==Parathyroid adenoma== |