Account-creators
1,040
edits
Difference between revisions of "Myeloproliferative neoplasms"
Jump to navigation
Jump to search
Myeloproliferative neoplasms (view source)
Revision as of 13:41, 9 December 2015
, 13:41, 9 December 2015polycythemia + image
Jensflorian (talk | contribs) (+images) |
Jensflorian (talk | contribs) (polycythemia + image) |
||
| Line 16: | Line 16: | ||
* enlarged spleen | * enlarged spleen | ||
* increased clotting | * increased clotting | ||
==Polycythemia vera== | |||
*ICD-O: 9950/3 | |||
*Median age: 60 years. | |||
*Median survival: >10years. | |||
*Typical course: | |||
**Prodromal stadium: Mild erythrocytosis. | |||
**Polycythemic phase: Incereased RBC count. | |||
**Post-polycythemic ("spent") phase: Ineffective hematopoiesis, bone marrow fibrosis. | |||
*Transformation in [[AML]] possible (2-3%). | |||
===Morphology=== | |||
*Panmyelosis. | |||
*Many megakaryocytes in bone marrow section. | |||
*Increased cellularity of bone marrow (35-100%). | |||
*Teardrop-RBC cells (dacryocytes) in late stage. | |||
*Fibrosis (reticulin stain). | |||
==Images== | ==Images== | ||
<gallery> | <gallery> | ||
File:Thrombocytosis.jpg | Thrombocythemia. Peripheral blood (WC/Erhabor Osario) | File:Thrombocytosis.jpg | Thrombocythemia. Peripheral blood (WC/Erhabor Osario) | ||
File:Polycythemia_vera,_blood_smear.jpg | Polycythemia vera. Peripheral blood (WC/AFIP) | File:Polycythemia_vera,_blood_smear.jpg | Polycythemia vera. Peripheral blood (WC/Orlandi Mourao) | ||
File:Teardrop Cells smear 2009-09-22.JPG | Teardrop RBC cells in polycythemia vera. Peripheral blood (WC/AFIP) | |||
File:Essential Thrombocythemia, Peripheral Blood (10189570483).jpg | Essential thrombocythemia. Peripheral blood (WC/Ed Uthman) | File:Essential Thrombocythemia, Peripheral Blood (10189570483).jpg | Essential thrombocythemia. Peripheral blood (WC/Ed Uthman) | ||
File:Essential thrombocythemia (2).jpg | Essential thrombocythemia. Bone marrow (WC/KGH) | File:Essential thrombocythemia (2).jpg | Essential thrombocythemia. Bone marrow (WC/KGH) | ||