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Difference between revisions of "Pseudomelanosis coli"
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***Melanosis coli. | ***Melanosis coli. | ||
**Old haemorrhage, i.e. hemosiderin-laden macrophages (may be demonstrated with ''[[Prussian blue stain]]''<ref>URL: [http://education.vetmed.vt.edu/curriculum/VM8054/labs/Lab2/Examples/exprussb.htm http://education.vetmed.vt.edu/curriculum/VM8054/labs/Lab2/Examples/exprussb.htm]. Accessed on: 5 May 2010.</ref>). | **Old haemorrhage, i.e. hemosiderin-laden macrophages (may be demonstrated with ''[[Prussian blue stain]]''<ref>URL: [http://education.vetmed.vt.edu/curriculum/VM8054/labs/Lab2/Examples/exprussb.htm http://education.vetmed.vt.edu/curriculum/VM8054/labs/Lab2/Examples/exprussb.htm]. Accessed on: 5 May 2010.</ref>). | ||
**Melanin (from melanocytes) - rare in colon (may be demonstrated with a ''[[Fontana-Masson stain]]''<ref>URL: [http://education.vetmed.vt.edu/curriculum/VM8054/labs/Lab2/Examples/exfontana.htm http://education.vetmed.vt.edu/curriculum/VM8054/labs/Lab2/Examples/exfontana.htm]. Accessed on: 5 May 2010.</ref> - | **Melanin (from melanocytes) - rare in colon (may be demonstrated with a ''[[Fontana-Masson stain]]''<ref>URL: [http://education.vetmed.vt.edu/curriculum/VM8054/labs/Lab2/Examples/exfontana.htm http://education.vetmed.vt.edu/curriculum/VM8054/labs/Lab2/Examples/exfontana.htm]. Accessed on: 5 May 2010.</ref>). | ||
***Fontana-Masson ''not'' useful for differentiating from pseudomelanosis, as pseudomelanosis is Fontana-Masson positive.<ref name=pmid2346038>{{Cite journal | last1 = Park | first1 = C. | last2 = Cho | first2 = NH. | last3 = Jeong | first3 = HJ. | title = Melanosis coli--histochemical and immunohistochemical comparison of the pigments of melanosis coli and Dubin-Johnson syndrome. | journal = Yonsei Med J | volume = 31 | issue = 1 | pages = 27-32 | month = Mar | year = 1990 | doi = | PMID = 2346038 }}</ref> | |||
**Foreign material (e.g. tattoo pigment) - not seen in GI tract. | **Foreign material (e.g. tattoo pigment) - not seen in GI tract. | ||