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Difference between revisions of "Non-small cell lung carcinoma"
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Non-small cell lung carcinoma (view source)
Revision as of 02:11, 19 November 2015
, 02:11, 19 November 2015no edit summary
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Consensus terminology from Travis ''et al''.:<ref name=pmid22970842>{{Cite journal | last1 = Travis | first1 = WD. | last2 = Brambilla | first2 = E. | last3 = Noguchi | first3 = M. | last4 = Nicholson | first4 = AG. | last5 = Geisinger | first5 = K. | last6 = Yatabe | first6 = Y. | last7 = Ishikawa | first7 = Y. | last8 = Wistuba | first8 = I. | last9 = Flieder | first9 = DB. | title = Diagnosis of lung cancer in small biopsies and cytology: implications of the 2011 International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification. | journal = Arch Pathol Lab Med | volume = 137 | issue = 5 | pages = 668-84 | month = May | year = 2013 | doi = 10.5858/arpa.2012-0263-RA | PMID = 22970842 }}</ref> | |||
{| class="wikitable sortable" | |||
! Diagnosis | |||
! Morphology | |||
! Stains | |||
|- | |||
| Non-small cell carcinoma, favour adenocarcinoma | |||
| undifferentiated morphology | |||
| TTF-1 +ve | |||
|- | |||
| Non-small cell carcinoma, favour squamous cell carcinoma | |||
| undifferentiated morphology | |||
| p40 or p63 +ve | |||
|- | |||
| Non-small cell carcinoma-not otherwise specified | |||
| undifferentiated morphology | |||
| -ve NE stains, -ve SCC stains, -ve adenoca stains | |||
|} | |||
<pre> | <pre> | ||
Lung, Left Lower Lobe, Core Biopsy: | Lung, Left Lower Lobe, Core Biopsy: | ||
- | - NON-SMALL CELL CARCINOMA-NOT OTHERWISE SPECIFIED, see comment. | ||
COMMENT: | COMMENT: | ||
| Line 108: | Line 127: | ||
squamous cell carcinoma. | squamous cell carcinoma. | ||
The neuroendocrine markers (chromogranin A, synaptophysin, CD56) and the | The neuroendocrine markers (chromogranin A, synaptophysin, CD56) and the squamous | ||
markers | markers (p63, CK5/6) are negative; thus, the tumour is not further classified. | ||
</pre> | </pre> | ||