Difference between revisions of "Lung tumours"

Lung tumours (view source)

779 bytes removed , 03:49, 18 November 2015

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 ==Poorly differentiated carcinoma==
-===General===
+{{Main|Poorly differentiated carcinoma of the lung}}
-*Should be used when the DDx is ''small cell carcinoma'' versus ''non-small cell carcinoma''.
-*''Poorly differentiated carcinoma'' leaves the surgical options on the table.
-===IHC===
-*Lack of staining with [[neuroendocrine markers]] (chromogranin A -ve, synaptophysin -ve, CD56 -ve).
-*Keratins +ve.
-===Sign out===
-<pre>
-Lung, Left Lower Lobe, Core Biopsy:
-- POORLY DIFFERENTIATED CARCINOMA, see comment.
-COMMENT:
-The tumour stains as follows:
-POSITIVE: EMA, AE1/AE3.
-NEGATIVE: TTF-1, chromogranin A, synaptophysin, CD56, CD45.
-The morphology would be compatible with small cell carcinoma or basaloid
-squamous cell carcinoma.
-The neuroendocrine markers (chromogranin A, synaptophysin, CD56) and the squamoid
-markers available (p63, CK5/6) are negative; thus, the tumour is not further classified.
-</pre>
 ==Lung metastasis==