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===General=== | ===General=== | ||
*Often abbreviated '''''LIP'''''. | *Often abbreviated '''''LIP'''''. | ||
*Associated with autoimmune disorders ([[rheumatoid arthritis]], pernicious anemia, Sjoegren syndrome) | *Associated with autoimmune disorders ([[rheumatoid arthritis]], pernicious anemia, Sjoegren syndrome)<ref>URL: [http://emedicine.medscape.com/article/299643-overview http://emedicine.medscape.com/article/299643-overview]. Accessed on: 2 June 2010.</ref> and immunodeficiency.<ref name=pmid16088689>{{cite journal |author=Nicholson AG |title=Lymphocytic interstitial pneumonia and other lymphoproliferative disorders in the lung |journal=Semin Respir Crit Care Med |volume=22 |issue=4 |pages=409–22 |year=2001 |month=August |pmid=16088689 |doi=10.1055/s-2001-17384 |url=}}</ref> | ||
*Associated with viral infections ([[HIV]], EBV, human T-cell leukemia virus (HTLV) type 1). | *Associated with viral infections ([[HIV]], EBV, human T-cell leukemia virus (HTLV) type 1). | ||
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Image: [http://www.scielo.br/img/revistas/jbpneu/v34n2/en_a02fig01.jpg LIP (scielo.br)]. | Image: [http://www.scielo.br/img/revistas/jbpneu/v34n2/en_a02fig01.jpg LIP (scielo.br)]. | ||
DDx: | |||
*Follicular bronchitis/bronchiolitis. | |||
**This is determined in part by radiology. | |||
==Follicular bronchitis/bronchiolitis== | |||
===General=== | |||
*Similar to [[lymphocytic interstitial pneumonia]] (LIP). | |||
**Overlaps with LIP.<ref name=pmid16088689>{{cite journal |author=Nicholson AG |title=Lymphocytic interstitial pneumonia and other lymphoproliferative disorders in the lung |journal=Semin Respir Crit Care Med |volume=22 |issue=4 |pages=409–22 |year=2001 |month=August |pmid=16088689 |doi=10.1055/s-2001-17384 |url=}}</ref> | |||
*Associated with the things seen in LIP;<ref>{{cite journal |author=Aerni MR, Vassallo R, Myers JL, Lindell RM, Ryu JH |title=Follicular bronchiolitis in surgical lung biopsies: clinical implications in 12 patients |journal=Respir Med |volume=102 |issue=2 |pages=307–12 |year=2008 |month=February |pmid=17997299 |doi=10.1016/j.rmed.2007.07.032 |url=}}</ref> however, associations may be less clear in children.<ref name=pmid8404188>{{cite journal |author=Kinane BT, Mansell AL, Zwerdling RG, Lapey A, Shannon DC |title=Follicular bronchitis in the pediatric population |journal=Chest |volume=104 |issue=4 |pages=1183–6 |year=1993 |month=October |pmid=8404188 |doi= |url=}}</ref> | |||
===Gross/radiology=== | |||
*No distinct nodule or mass. | |||
===Microscopic=== | |||
Features: | |||
*Peribronchiolar/peribronchial lymphoid nodules: | |||
**Reactive germinal centres. | |||
**Plasma cells. | |||
*+/-Lymphoid nodules in the interlobular septa. | |||
=Smoking assoc. disease= | =Smoking assoc. disease= |
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