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| Caption = Proliferative fibrocystic changes (''florid epithelial hyperplasia'' together with ''fibrocystic breast changes''). [[H&E stain]]. | | Caption = Proliferative fibrocystic changes (''florid epithelial hyperplasia'' together with ''fibrocystic breast changes''). [[H&E stain]]. | ||
| Synonyms = florid epithelial hyperplasia of the usual type, usual ductal hyperplasia, moderate epithelial hyperplasia | | Synonyms = florid epithelial hyperplasia of the usual type, usual ductal hyperplasia, moderate epithelial hyperplasia | ||
| Micro = breast glands with more than four cell layers above the basement membrane with irregular cell spacing (e.g. streaming), slit-like lumina (esp. at the periphery of the duct), no [[DCIS]]-like architecture (not cribriform, not papillary, not micropapillary, not solid), no nuclear atypia - usually no [[nucleoli]] | | Micro = breast glands with more than four cell layers above the basement membrane with irregular cell spacing (e.g. streaming), slit-like lumina (esp. at the periphery of the duct), no [[DCIS]]-like architecture (not [[cribriform]], not papillary, not micropapillary, not solid), no nuclear atypia - usually no [[nucleoli]] | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[mild epithelial hyperplasia]], [[atypical ductal hyperplasia]], cribriform [[ductal carcinoma in situ]] | | LMDDx = [[mild epithelial hyperplasia]], [[atypical ductal hyperplasia]], cribriform [[ductal carcinoma in situ]] | ||
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*Irregular cell spacing; streaming. | *Irregular cell spacing; streaming. | ||
*Slit-like lumina, esp. at the periphery of the duct. | *Slit-like lumina, esp. at the periphery of the duct. | ||
*No [[DCIS]]-like architecture (not cribriform, not papillary, not micropapillary, not solid). | *No [[DCIS]]-like architecture (not [[cribriform]], not papillary, not micropapillary, not solid). | ||
*No nuclear atypia - usually no [[nucleoli]]. | *No nuclear atypia - usually no [[nucleoli]]. | ||
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