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Difference between revisions of "Lung transplant pathology"
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Lung transplant pathology (view source)
Revision as of 19:35, 10 February 2011
, 19:35, 10 February 2011more on classification
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'''Lung transplant pathology''' is a little subspecialty in the subspecialty of [[lung]] pathology. | '''Lung transplant pathology''' is a little subspecialty in the subspecialty of [[lung]] pathology. | ||
==Classification - rejection== | |||
Types:<ref name=pmid18096473>{{cite journal |author=Stewart S, Fishbein MC, Snell GI, ''et al.'' |title=Revision of the 1996 working formulation for the standardization of nomenclature in the diagnosis of lung rejection |journal=J. Heart Lung Transplant. |volume=26 |issue=12 |pages=1229–42 |year=2007 |month=December |pmid=18096473 |doi=10.1016/j.healun.2007.10.017 |url=}}</ref> | |||
*A. Acute rejection. | |||
**A0 (none), A1 (minimal), A2 (mild), A3 (moderate), A4 (severe). | |||
*B. Small airway inflammation/lymphocytic bronchiolitis. | |||
**B0 (none), B1R (low-grade), B2R (high-grade), BX (cannot be graded). | |||
*C. Chronic airway rejection - broncholitis obliterans. | |||
**C0 (absent), C1 (present). | |||
*D. Chronic vascular rejection. | |||
==Rejection== | ==Rejection== | ||
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===Microscopic=== | ===Microscopic=== | ||
Features:<ref>{{Ref PPP|407}}</ref> | Features:<ref name=Ref_PPP407>{{Ref PPP|407}}</ref> | ||
*Perivascular lymphocytes / plasmacytoid cells. | *Perivascular lymphocytes / plasmacytoid cells. | ||
*+/-Macrophages. | *+/-Macrophages. | ||
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*[http://commons.wikimedia.org/wiki/File:Lung_transplant_rejection_-_intermed_mag.jpg Rejection - intermed. mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Lung_transplant_rejection_-_intermed_mag.jpg Rejection - intermed. mag. (WC)]. | ||
*[http://commons.wikimedia.org/wiki/File:Lung_transplant_rejection_-_very_high_mag.jpg Rejection - very high mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Lung_transplant_rejection_-_very_high_mag.jpg Rejection - very high mag. (WC)]. | ||
==Post-transplant lymphoproliferative disorder== | |||
{{Main|Post-transplant lymphoproliferative disorder}} | |||
*A rare complication of transplants. | |||
*Similar to [[DLBCL]]. | |||
==See also== | ==See also== | ||
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==References== | ==References== | ||
{{reflist| | {{reflist|2}} | ||
[[Category:Pulmonary pathology]] | [[Category:Pulmonary pathology]] | ||