Difference between revisions of "Talk:Congenital heart disease"

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→‎TOF: new section
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===Final diagnosis===
===Final diagnosis===
Heart, atrial septum, septectomy - Mild endocardial fibroelastosis and mild hypertrophic changes.
Heart, atrial septum, septectomy - Mild endocardial fibroelastosis and mild hypertrophic changes.
== TOF ==
===Microscopic description===
A. The section shows thymus with normal cortical and medullary development. The corticomedullary junction is well demarcated; however, there is an increase in histiocytes within the cortex and focal degenerative changes of thymic corpuscles. There is no depletion of cortical lymphocytes.
B. The sections show fragments of normal cardiac myocytes, in part, covered by benign endothelial cells, and, focally, thick bands of fibrous tissue and fibroelastic tissue. There is no inflammation and no haphazard arrangement of muscle fibres.
There is an unremarkable piece of a large elastic artery, with attached connective tissue (consisting predominantly of adipocytes, some fibrous tissue and fragments of nerve). 
There are fragments of laminated connective tissue covered by endothelium, consisting of fibrous tissue, elastic fibres, and scant myxomatous material (possible valve fragment).
===Final diagnosis===
A. Thymus, incidental thymectomy - Architecturally normal thymus with mild physiologic stress effects.
B. Cardiac muscle, right ventricle musle bundle (RVMB), biopsy -
i) Cardiac muscle with fibroelastosis and endocardial fibrosis.
ii) Large elastic artery with attached connective tissue.
iii) Valve-like material (see microscopic description).
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