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Difference between revisions of "Pleural invasion"
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[[Image:Lung adenocarcinoma visceral pleural invasion -- intermed mag.jpg|thumb|right|Visceral pleural invasion. [[H&E stain]]. (WC)]] | [[Image:Lung adenocarcinoma visceral pleural invasion -- intermed mag.jpg|thumb|right|Visceral pleural invasion. [[H&E stain]]. (WC)]] | ||
'''Pleural invasion''' is the presence of tumour in the [[pleura]]. Pleural invasion is considered a poor prognosticator in [[lung cancer]],<ref name=pmid19057261>{{Cite journal | last1 = Travis | first1 = WD. | last2 = Brambilla | first2 = E. | last3 = Rami-Porta | first3 = R. | last4 = Vallières | first4 = E. | last5 = Tsuboi | first5 = M. | last6 = Rusch | first6 = V. | last7 = Goldstraw | first7 = P. | title = Visceral pleural invasion: pathologic criteria and use of elastic stains: proposal for the 7th edition of the TNM classification for lung cancer. | journal = J Thorac Oncol | volume = 3 | issue = 12 | pages = 1384-90 | month = Dec | year = 2008 | doi = 10.1097/JTO.0b013e31818e0d9f | PMID = 19057261 }}</ref><ref name=pmid15999057>{{Cite journal | last1 = Shimizu | first1 = K. | last2 = Yoshida | first2 = J. | last3 = Nagai | first3 = K. | last4 = Nishimura | first4 = M. | last5 = Ishii | first5 = G. | last6 = Morishita | first6 = Y. | last7 = Nishiwaki | first7 = Y. | title = Visceral pleural invasion is an invasive and aggressive indicator of non-small cell lung cancer. | journal = J Thorac Cardiovasc Surg | volume = 130 | issue = 1 | pages = 160-5 | month = Jul | year = 2005 | doi = 10.1016/j.jtcvs.2004.11.021 | PMID = 15999057 }}</ref> and important in determining the tumour stage in [[lung cancer staging]]. | '''Pleural invasion''' is the presence of tumour in the [[pleura]]. Pleural invasion is considered a poor prognosticator in [[lung cancer]],<ref name=pmid19057261>{{Cite journal | last1 = Travis | first1 = WD. | last2 = Brambilla | first2 = E. | last3 = Rami-Porta | first3 = R. | last4 = Vallières | first4 = E. | last5 = Tsuboi | first5 = M. | last6 = Rusch | first6 = V. | last7 = Goldstraw | first7 = P. | title = Visceral pleural invasion: pathologic criteria and use of elastic stains: proposal for the 7th edition of the TNM classification for lung cancer. | journal = J Thorac Oncol | volume = 3 | issue = 12 | pages = 1384-90 | month = Dec | year = 2008 | doi = 10.1097/JTO.0b013e31818e0d9f | PMID = 19057261 }}</ref><ref name=pmid15999057>{{Cite journal | last1 = Shimizu | first1 = K. | last2 = Yoshida | first2 = J. | last3 = Nagai | first3 = K. | last4 = Nishimura | first4 = M. | last5 = Ishii | first5 = G. | last6 = Morishita | first6 = Y. | last7 = Nishiwaki | first7 = Y. | title = Visceral pleural invasion is an invasive and aggressive indicator of non-small cell lung cancer. | journal = J Thorac Cardiovasc Surg | volume = 130 | issue = 1 | pages = 160-5 | month = Jul | year = 2005 | doi = 10.1016/j.jtcvs.2004.11.021 | PMID = 15999057 }}</ref> and important in determining the tumour stage in [[lung cancer staging]]. | ||
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==Stains== | ==Stains== | ||
[[Image:Lung adenocarcinoma visceral pleural invasion - Miller - alt -- high mag.jpg|thumb|right|Visceral pleural invasion. [[Miller stain]]. (WC)]] | |||
*Elastic stain (e.g. [[Miller stain|Miller]], [[Elastic trichrome stain|elastic trichrome]], [[Verhoeff-van Gieson stain|Verhoeff-van Gieson]]) - demonstrating tumour superficial to the (external) elastica. | *Elastic stain (e.g. [[Miller stain|Miller]], [[Elastic trichrome stain|elastic trichrome]], [[Verhoeff-van Gieson stain|Verhoeff-van Gieson]]) - demonstrating tumour superficial to the (external) elastica. | ||
===Images=== | |||
<gallery> | |||
Image: Lung adenocarcinoma visceral pleural invasion - Miller -- very low mag.jpg | Adenocarcinoma - VPI - Miller - very low mag. | |||
Image: Lung adenocarcinoma visceral pleural invasion - Miller -- low mag.jpg | Adenocarcinoma - VPI - Miller - low mag. | |||
Image: Lung adenocarcinoma visceral pleural invasion - Miller -- intermed mag.jpg | Adenocarcinoma - VPI - Miller - intermed. mag. | |||
Image: Lung adenocarcinoma visceral pleural invasion - Miller - alt -- intermed mag.jpg | Adenocarcinoma - VPI - Miller - intermed. mag. | |||
Image: Lung adenocarcinoma visceral pleural invasion - Miller -- high mag.jpg | Adenocarcinoma - VPI - Miller - high mag. | |||
Image: Lung adenocarcinoma visceral pleural invasion - Miller - alt -- high mag.jpg | Adenocarcinoma - VPI - Miller - high mag. | |||
Image: Lung adenocarcinoma visceral pleural invasion - Miller -- very high mag.jpg | Adenocarcinoma - VPI - Miller - very high mag. | |||
</gallery> | |||
==See also== | ==See also== | ||