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→Inflammatory myopathy: table overview + exemplary images
Jensflorian (talk | contribs) (→Inflammatory myopathy: DDx) |
Jensflorian (talk | contribs) (→Inflammatory myopathy: table overview + exemplary images) |
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#*Rare. | #*Rare. | ||
'''Quick overview:''' | |||
{| class="wikitable" | |||
| | |||
| '''Dermatomyositis''' | |||
| '''Polymyositis''' | |||
| '''sporadic Inclusion body myositis | |||
|- | |||
| Myositis type | |||
| Perifascicular | |||
| Diffuse | |||
| Diffuse (limited inflammation) | |||
|- | |||
| Histology | |||
| Perivascular inflammation, Perifascicular damage. | |||
| Endomysial inflammation and damage. | |||
| Endomysial inflammation, rimmed vacuoles withe eosinophilic inclusions, neurogenic changes. | |||
|- | |||
| Immunostaining | |||
| CD4+ B-cell lymphocytes predominate, C5b9 complement complex deposits in capillaries. | |||
| CD8+ lymphocytes invading non-necrotic fibers. | |||
| Mainly CD8-positive lymphocytes. | |||
|- | |||
| Electron microscopy | |||
| Tubulovesicular inclusions. | |||
| Nothing special. | |||
| Filamentous inclusions. | |||
|- | |||
| Exemplary image | |||
|[[File:Dermatomyositis_muscle_biopsy_HE.jpg | center | thumb]] | |||
|[[File:Polymyositis_muscle_biopsy_HE.jpg | center | thumb]] | |||
|[[File:IBM rimmed vacuoles HE x200.jpg | center | thumb]] | |||
|} | |||
===Partial invasion of muscle fibres=== | ===Partial invasion of muscle fibres=== | ||