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Difference between revisions of "Germ cell tumours"
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→Choriocarcinoma
m (→Clinical) |
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| Line 92: | Line 92: | ||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*'''C'''ytotrophoblasts - '''key feature'''. | |||
*'''C'''ytotrophoblasts | |||
**'''C'''lear cytoplasm. | **'''C'''lear cytoplasm. | ||
**Polygonal shaped cells in cords/masses. | **Polygonal shaped cells in cords/masses. | ||
| Line 102: | Line 99: | ||
*+/-Hemorrhage. | *+/-Hemorrhage. | ||
*+/-Necrosis. | *+/-Necrosis. | ||
*Syncytiotrophoblasts - may be absent.<ref>URL: [http://www.webpathology.com/image.asp?n=4&Case=36 http://www.webpathology.com/image.asp?n=4&Case=36]. Accessed on: 8 February 2011.</ref> | |||
**Large + many irreg. or lobular hyperchromatic nuclei. | |||
**Eosinophilic vacuolated cytoplasm (contains hCG). | |||
Image(s): | Image(s): | ||
*[http://www.webpathology.com/image.asp?case=36&n=1 Choriocarcinoma (webpathology.com)] | *[http://www.webpathology.com/image.asp?n=5&Case=36 Choriocarcinoma - low mag. (webpathology.com)]. | ||
*[http://www.webpathology.com/image.asp?case=36&n=1 Choriocarcinoma (webpathology.com)]. | |||
*[http://www.webpathology.com/image.asp?n=4&Case=36 Choriocarcinoma (webpathology.com)]. | |||
Notes: | Notes: | ||