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Difference between revisions of "Oligodendroglioma"
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File:Oligodendroglioma_discrete_invasion_HE.jpg | Discrete invasion in a oligodendroglioma. (WC/jensflorian) | File:Oligodendroglioma_discrete_invasion_HE.jpg | Discrete invasion in a oligodendroglioma. (WC/jensflorian) | ||
File:Anaplastic_oligodendroglioma_minigemistocytes.jpg | Minigemistocytes and mitoses. (WC/jensflorian) | File:Anaplastic_oligodendroglioma_minigemistocytes.jpg | Minigemistocytes and mitoses. (WC/jensflorian) | ||
MAP2_anaplastic_oligodendroglioma.jpg | Perinuclear MAP2 immunoreactivity in oligodendroglioma. (WC/jensflorian) | MAP2_anaplastic_oligodendroglioma.jpg | Perinuclear [[MAP2]] immunoreactivity in oligodendroglioma. (WC/jensflorian) | ||
File:IDH1_R132H_in_anaplastic_ologodendroglioma.jpg | Demonstration of IDH1 R132H mutation in oligodendroglioma. (WC/jensflorian) | File:IDH1_R132H_in_anaplastic_ologodendroglioma.jpg | Demonstration of [[IDH-1|IDH1 R132H]] mutation in oligodendroglioma. (WC/jensflorian) | ||
</gallery> | </gallery> | ||
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==IHC== | ==IHC== | ||
Features: | Features: | ||
* | *[[MAP2]] +ve.<reF name=pmid12025943>{{cite journal |author=Suzuki SO, Kitai R, Llena J, Lee SC, Goldman JE, Shafit-Zagardo B |title=MAP-2e, a novel MAP-2 isoform, is expressed in gliomas and delineates tumor architecture and patterns of infiltration |journal=J. Neuropathol. Exp. Neurol. |volume=61 |issue=5 |pages=403–12 |year=2002 |month=May |pmid=12025943 |doi= |url=}}</ref> | ||
*GFAP +ve (variable). | *GFAP +ve (variable). | ||
**Some subtypes +ve - should not be used to distinguish.<ref name=Ref_PSNP>{{Ref PSNP|98}}</ref> | **Some subtypes +ve - should not be used to distinguish.<ref name=Ref_PSNP>{{Ref PSNP|98}}</ref> | ||