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Comment: Glioblastoma (GBM) is the most common malignant brain tumour. Primary GBM usually do not harbor any IDH1/2 and ATRX alterations, while secondary GBM that develop from lower-grade precursor lesions usaually show nuclear [[ATRX]] loss and positive [[IDH-1]] immunostaining. | Comment: Glioblastoma (GBM) is the most common malignant brain tumour. Primary GBM usually do not harbor any IDH1/2 and ATRX alterations, while secondary GBM that develop from lower-grade precursor lesions usaually show nuclear [[ATRX]] loss and positive [[IDH-1]] immunostaining. | ||
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===Other cases=== | ===Other cases=== | ||
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