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Difference between revisions of "Parathyroid glands"
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→Parathyroid carcinoma
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Features:<ref>{{Ref PBoD8|1128}}</ref> | Features:<ref>{{Ref PBoD8|1128}}</ref> | ||
*Histologically normal parathyroid cells. | *Histologically normal parathyroid cells. | ||
**Cytologic features not reliable for diagnosis. | **Cytologic features '''not''' reliable for diagnosis. | ||
*Fibrous capsule. | *Fibrous capsule. | ||
*Invasion of surrounding tissue - '''key feature'''. | *Invasion of surrounding tissue - '''key feature'''. | ||
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===IHC=== | ===IHC=== | ||
*Ki-67 >6% of cells positive - | *Ki-67 >6% of cells positive - supports diagnosis.<ref name=pmid7860042>{{Cite journal | last1 = Abbona | first1 = GC. | last2 = Papotti | first2 = M. | last3 = Gasparri | first3 = G. | last4 = Bussolati | first4 = G. | title = Proliferative activity in parathyroid tumors as detected by Ki-67 immunostaining. | journal = Hum Pathol | volume = 26 | issue = 2 | pages = 135-8 | month = Feb | year = 1995 | doi = | PMID = 7860042 }}</ref> | ||
**Parathyroid adenomas and hyperplasias ~ 3%. | **Parathyroid adenomas and hyperplasias ~ 3%. | ||