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Difference between revisions of "Sarcomatoid carcinoma of the prostate"
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Sarcomatoid carcinoma of the prostate (view source)
Revision as of 03:40, 9 February 2016
, 03:40, 9 February 2016no edit summary
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| Molecular = | | Molecular = | ||
| IF = | | IF = | ||
| Gross = | | Gross = | ||
| | | Grossing = [[prostate biopsy]], [[prostate chips]], [[radical prostatectomy]] | ||
| Staging = [[prostate cancer staging]] | |||
| Site = [[prostate gland]] - see ''[[prostate carcinoma]]'' | | Site = [[prostate gland]] - see ''[[prostate carcinoma]]'' | ||
| Assdx = | | Assdx = | ||
| Line 38: | Line 39: | ||
==Microscopic== | ==Microscopic== | ||
Features:<ref name=Ref_GUP80>{{Ref GUP|77 & 80}}</ref> | Features:<ref name=Ref_GUP80>{{Ref GUP|77 & 80}}</ref> | ||
* | *Typically a biphasic tumour: | ||
*#Spindle cells (sarcomatous component). | *#Spindle cells (sarcomatous component). | ||
*#*May include components of: [[osteosarcoma]], [[chondrosarcoma]] and/or [[rhabdomyosarcoma]]. | *#*May include components of: [[osteosarcoma]], [[chondrosarcoma]] and/or [[rhabdomyosarcoma]]. | ||
*#Epithelial (glandular) component (like conventional prostate carcinoma). | *#Epithelial (glandular) component (like conventional prostate carcinoma). | ||
*#*May be absent. ‡ | |||
Note: | |||
* ‡ The history is should be compelling or the tumour keratin positive, if no epithelial component is present. | |||
DDx: | DDx: | ||
*[[Sarcomatoid urothelial carcinoma]]. | *[[Sarcomatoid urothelial carcinoma]]. | ||
*[[Sarcoma]]. | *[[Sarcoma]], e.g. [[rhabdomyosarcoma]], [[liposarcoma]], [[leiomyosarcoma]]. | ||
===Images=== | ===Images=== | ||
| Line 64: | Line 68: | ||
Image: Conventional prostate carcinoma -- high mag.jpg | SCP - intermed. mag. | Image: Conventional prostate carcinoma -- high mag.jpg | SCP - intermed. mag. | ||
</gallery> | </gallery> | ||
==IHC== | ==IHC== | ||
Features - typical:<ref name=Ref_GUP80>{{Ref GUP|77 & 80}}</ref> | Features - typical:<ref name=Ref_GUP80>{{Ref GUP|77 & 80}}</ref> | ||