Difference between revisions of "Renal hybrid oncocytic/chromophobe tumour"

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# Renal oncocytoma with scattered chromophobe cells.
# Renal oncocytoma with scattered chromophobe cells.
# Large eosinophilic cell with intracytoplasmic vacuoles.
# Large eosinophilic cell with intracytoplasmic vacuoles.
#* Prominent nucleoli ([[ISUP nucleolar grade]] 3).
#* Perinuclear halos (occasional).
#* Nested architecture.


DDx:
DDx:
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Features:
Features:
*CD117 +ve (practically definitional<ref name=pmid23740406/>).
*CD117 +ve (practically definitional<ref name=pmid23740406/>).
*CK7 +ve - may be variable.<ref name=pmid23708994/>
*CK7 +ve - often variable/patchy (oncocytoma-like).<ref name=pmid23708994/>
 
Others:
*Vimentin -ve.
*EMA +ve.
*CD10 +ve.
*PAX8 +ve.


==Molecular==
==Molecular==
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