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Difference between revisions of "Renal hybrid oncocytic/chromophobe tumour"
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Renal hybrid oncocytic/chromophobe tumour (view source)
Revision as of 14:44, 15 June 2015
, 14:44, 15 June 2015no edit summary
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*Rare. | *Rare. | ||
*Molecular heterogeneous group<ref name=pmid23740406/> - may represent several different entities. | *Molecular heterogeneous group<ref name=pmid23740406/> - may represent several different entities. | ||
*Prognosis good - based on one series of 11 cases.<ref name=pmid23708994/> | |||
May be seen in several contexts:<ref name=pmid23740406/> | May be seen in several contexts:<ref name=pmid23740406/> | ||
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*Other [[renal tumours with eosinophilic cytoplasm]]. | *Other [[renal tumours with eosinophilic cytoplasm]]. | ||
*[[Renal cell carcinoma, unclassified]]. | *[[Renal cell carcinoma, unclassified]]. | ||
==Stains== | |||
Features:<ref name=pmid23708994>{{Cite journal | last1 = Poté | first1 = N. | last2 = Vieillefond | first2 = A. | last3 = Couturier | first3 = J. | last4 = Arrufat | first4 = S. | last5 = Metzger | first5 = I. | last6 = Delongchamps | first6 = NB. | last7 = Camparo | first7 = P. | last8 = Mège-Lechevallier | first8 = F. | last9 = Molinié | first9 = V. | title = Hybrid oncocytic/chromophobe renal cell tumours do not display genomic features of chromophobe renal cell carcinomas. | journal = Virchows Arch | volume = 462 | issue = 6 | pages = 633-8 | month = Jun | year = 2013 | doi = 10.1007/s00428-013-1422-4 | PMID = 23708994 }}</ref> | |||
*[[Hale's colloidal iron]] +ve (apical pattern). | |||
==IHC== | ==IHC== | ||
Features: | Features: | ||
*CD117 +ve (practically definitional). | *CD117 +ve (practically definitional<ref name=pmid23740406/>). | ||
*CK7 +ve | *CK7 +ve - may be variable.<ref name=pmid23708994/> | ||
==Molecular== | |||
*No features characteristic of [[chromophobe RCC]] on array-CGH analysis.<ref name=pmid23708994/> | |||
==See also== | ==See also== | ||
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==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Genitourinary pathology]] | [[Category:Genitourinary pathology]] | ||
[[Category:Diagnosis]] | |||