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Difference between revisions of "Medical lung diseases"
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→Hypersensitivity pneumonitis: expand HP
(→Asbestosis: make own section) |
(→Hypersensitivity pneumonitis: expand HP) |
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*AKA ''extrinsic allergic alveolitis'' | *AKA ''extrinsic allergic alveolitis'' | ||
*Exposure to stuffs... e.g. moldy hay - ''Farmer's lung'', atypical mycobacteria - ''hot tub lung''. | *Exposure to stuffs... e.g. moldy hay - ''Farmer's lung'', atypical mycobacteria - ''hot tub lung''. | ||
*Upper lung predominant disease (???). | |||
===Microscopic=== | |||
Features: | |||
* Granulomata (not typically seen in UIP) - '''key feature'''.<ref name=pmid16061708>PMID 16061708.</ref> | |||
* Lesions have centrilobular prominence - '''key feature'''. <ref name=pmid16061708> | |||
** Allergens enter lung through airway which has a centrilobular location. | |||
* Chronic interstitial inflammation consisting primarily of lymphocytes. | |||
* Interstitial fibrosis. | |||
* Air space involvement (alveolitis). | |||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Hypersensitivity_pneumonitis_intermed_mag.jpg Hypersensitivity pneumonitis - intermed. mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Hypersensitivity_pneumonitis_high_mag.jpg Hypersensitivity pneumonitis - high mag. (WC)]. | |||
===IHC=== | ===IHC=== | ||
Nodules | Nodules positive for: | ||
*S-100. | *S-100. | ||
*CD1a. | *CD1a. | ||