Difference between revisions of "Congenital heart disease"

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==Eisenmenger syndrome==
==Eisenmenger syndrome==
===General===
Definition:<ref name=pmid19416617>{{cite journal |author=Jensen AS, Iversen K, Vejlstrup NG, Hansen PB, Sondergaard L |title=[Eisenmenger syndrome] |language=Danish |journal=Ugeskr. Laeg. |volume=171 |issue=15 |pages=1270-5 |year=2009 |month=April |pmid=19416617 |doi= |url=}}</ref>
Definition:<ref name=pmid19416617>{{cite journal |author=Jensen AS, Iversen K, Vejlstrup NG, Hansen PB, Sondergaard L |title=[Eisenmenger syndrome] |language=Danish |journal=Ugeskr. Laeg. |volume=171 |issue=15 |pages=1270-5 |year=2009 |month=April |pmid=19416617 |doi= |url=}}</ref>
*Pulmonary arterial hypertension with a
*[[Pulmonary arterial hypertension]] with a
*Right-to-left shunt (that was initially left-to-right), and  
*Right-to-left shunt (that was initially left-to-right), and  
*Cyanosis.
*Cyanosis.


Note: Eisenmenger syndrome, by definition in some sources, is (only) due to a VSD.
====Causes====
 
Causes:
*ASD - rarely causes Eisenmenger syndrome.
*ASD - rarely causes Eisenmenger syndrome.
*VSD.
*VSD.
*Extra-cardiac shunt.
*Extra-cardiac shunt.


*End-stage disease often characterized by fibrinoid [[necrosis]] of small pulmonary arterial vessels (arterioles & small arteries).<ref name=pmid12140128>{{cite journal |author=Daliento L, Rebellato L, Angelini A, ''et al.'' |title=Fatal outcome in Eisenmenger syndrome |journal=Cardiovasc. Pathol. |volume=11 |issue=4 |pages=221-8 |year=2002 |pmid=12140128 |doi= |url=}}</ref>
Note: Eisenmenger syndrome, by definition in some sources, is (only) due to a VSD.
 
===Microscopic===
End-stage disease:<ref name=pmid12140128>{{cite journal |author=Daliento L, Rebellato L, Angelini A, ''et al.'' |title=Fatal outcome in Eisenmenger syndrome |journal=Cardiovasc. Pathol. |volume=11 |issue=4 |pages=221-8 |year=2002 |pmid=12140128 |doi= |url=}}</ref>
*Often characterized by fibrinoid [[necrosis]] of small pulmonary arterial vessels (arterioles & small arteries).


==Cor pulmonale==
==Cor pulmonale==
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