Account-creators
186
edits
(→UNIT 2) |
|||
Line 75: | Line 75: | ||
{{hidden|Translate the following: c.1524_1527delCGTA.|<center>[[a small deletion of CGTA between the 1524 and 1527 base pairs]]</center>}} | {{hidden|Translate the following: c.1524_1527delCGTA.|<center>[[a small deletion of CGTA between the 1524 and 1527 base pairs]]</center>}} | ||
{{hidden|List 5 features of SNPs.|<center>[[most common DNA sequence variation in humans, must occur in >=1% of a particular population, frequency of SNPs varies by groups, but responsible for >90% of human genetic variation, an can be found in any region of genome]]</center>}} | {{hidden|List 5 features of SNPs.|<center>[[most common DNA sequence variation in humans, must occur in >=1% of a particular population, frequency of SNPs varies by groups, but responsible for >90% of human genetic variation, an can be found in any region of genome]]</center>}} | ||
{{hidden|Define a regulatory SNP and a synonymous SNP?|<center>[[Regulatory SNP: occur in non-coding regions e.g. promoters where they affect mRNA expression and stability, as occur in the splice site where can result in abnormal protein production]</center>}} | {{hidden|Define a regulatory SNP and a synonymous SNP?|<center>[[Regulatory SNP: occur in non-coding regions e.g. promoters where they affect mRNA expression and stability, as occur in the splice site where can result in abnormal protein production]]</center>}} | ||
{{hidden|What is the difference between a microstalellite and a minisattelite?|<center>[[Microsatellite = stretches of DNA with sequences of 2-4 base pairs repeated a few dozen times (STRP), minisatellite = variable number of tandem repeats 10-100bp in lenght]]</center>}} | {{hidden|What is the difference between a microstalellite and a minisattelite?|<center>[[Microsatellite = stretches of DNA with sequences of 2-4 base pairs repeated a few dozen times (STRP), minisatellite = variable number of tandem repeats 10-100bp in lenght]]</center>}} | ||
{{hidden|Describe Hardy-Weinberg Equilibrium?|<center>[[Mathematical probability function to describe allelic and genotype frequency in a random mating scenario]]</center>}} | {{hidden|Describe Hardy-Weinberg Equilibrium?|<center>[[Mathematical probability function to describe allelic and genotype frequency in a random mating scenario]]</center>}} |