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Difference between revisions of "Adrenal cortical adenoma"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Primary aldosteronism (1) adrenocortical adenoma.jpg | |||
| Width = | |||
| Caption = Adrenal cortical adenoma. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = | |||
| Subtypes = | |||
| LMDDx = adrenal cortical nodule, [[adrenal cortical hyperplasia]], [[adrenal cortical carcinoma]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[adrenal gland]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = relatively common | |||
| Bloodwork = | |||
| Rads = adrenal mass, HU<10 | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Adrenal cortical adenoma''', also '''adrenocortical adenoma''' and '''adrenal adenoma''', is a relatively common benign pathology of the [[adrenal gland]]. | '''Adrenal cortical adenoma''', also '''adrenocortical adenoma''' and '''adrenal adenoma''', is a relatively common benign pathology of the [[adrenal gland]]. | ||
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*Can be a cause of [[hypertension]].<ref name=pmid18584586/> | *Can be a cause of [[hypertension]].<ref name=pmid18584586/> | ||
*Radiologists are good at identifying adenomas, as they are usually lipid rich and have a characteristic low HU signal | *Radiologists are good at identifying adenomas, as they are usually lipid rich and have a characteristic low HU signal (<10 HU<ref name=pmid24636681>{{Cite journal | last1 = Tenenbaum | first1 = F. | last2 = Lataud | first2 = M. | last3 = Groussin | first3 = L. | title = [Update in adrenal imaging]. | journal = Presse Med | volume = 43 | issue = 4 Pt 1 | pages = 410-9 | month = Apr | year = 2014 | doi = 10.1016/j.lpm.2014.02.002 | PMID = 24636681 }}</ref>). | ||
**Microadenomas may be missed.<ref name=pmid18584586/><ref name=pmid20881759>{{Cite journal | last1 = Fujiwara | first1 = M. | last2 = Murao | first2 = K. | last3 = Imachi | first3 = H. | last4 = Yoshida | first4 = K. | last5 = Muraoka | first5 = T. | last6 = Ohyama | first6 = T. | last7 = Kushida | first7 = Y. | last8 = Haba | first8 = R. | last9 = Kakehi | first9 = Y. | title = Misdiagnosis of two cases of primary aldosteronism owing to failure of computed tomography to detect adrenal microadenoma. | journal = Am J Med Sci | volume = 340 | issue = 4 | pages = 335-7 | month = Oct | year = 2010 | doi = 10.1097/MAJ.0b013e3181e95587 | PMID = 20881759 }}</ref> | **Microadenomas may be missed.<ref name=pmid18584586/><ref name=pmid20881759>{{Cite journal | last1 = Fujiwara | first1 = M. | last2 = Murao | first2 = K. | last3 = Imachi | first3 = H. | last4 = Yoshida | first4 = K. | last5 = Muraoka | first5 = T. | last6 = Ohyama | first6 = T. | last7 = Kushida | first7 = Y. | last8 = Haba | first8 = R. | last9 = Kakehi | first9 = Y. | title = Misdiagnosis of two cases of primary aldosteronism owing to failure of computed tomography to detect adrenal microadenoma. | journal = Am J Med Sci | volume = 340 | issue = 4 | pages = 335-7 | month = Oct | year = 2010 | doi = 10.1097/MAJ.0b013e3181e95587 | PMID = 20881759 }}</ref> | ||
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*Most of the nuclei are bland, central and round. | *Most of the nuclei are bland, central and round. | ||
*May have foci of [[necrosis]]/degeneration and nuclear atypia. | *May have foci of [[necrosis]]/degeneration and nuclear atypia. | ||
Note: | Note: | ||
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**Hyperplasia is multifocal.<ref>IAV. 18 February 2009.</ref> | **Hyperplasia is multifocal.<ref>IAV. 18 February 2009.</ref> | ||
*[[Adrenal cortical carcinoma]]. | *[[Adrenal cortical carcinoma]]. | ||
===Images=== | |||
<gallery> | |||
Image: Adrenal CorticalAdenoma DSCN5001 PA.JPG|Adrenal Cortical Adenoma (SKB) | |||
Image: Adrenal CorticalAdenoma DSCN5002 PA.JPG|Adrenal Cortical Adenoma (SKB) | |||
Image: Adrenal CorticalAdenoma DSCN5004 PA.JPG|Adrenal Cortical Adenoma (SKB) | |||
Image: Adrenal CorticalAdenoma DSCN5005 PA.JPG|Adrenal Cortical Adenoma (SKB) | |||
Image: Adrenal CorticalAdenoma MP CTR.jpg|Adrenal Cortical Adenoma - Medium power (SKB) | |||
Image: Adrenal CorticalAdenoma HP CTR.jpg|Adrenal Cortical Adenoma - High power. Abundant clear cytoplasm. Round, regular nuclei. (SKB) | |||
Image: Adrenal CorticalAdenoma MP PA.JPG|Adrenal Cortical Adenoma - Some pleomorphism - Medium power (SKB) | |||
Image: Adrenal LipoAdenoma MP PA.JPG|Adrenal cortical adenoma with fat - "lipoadenoma" (SKB) | |||
</gallery> | |||
==See also== | ==See also== | ||