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Difference between revisions of "Talk:Esophagus"
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→Eosinophilic esophagitis: new section
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====Comment==== | ====Comment==== | ||
The histomorphologic findings are compatible with inflammatory bowel disease. There are no histomorphologic findings to suggest an infective etiology; however, this cannot be definitively excluded. | The histomorphologic findings are compatible with inflammatory bowel disease. There are no histomorphologic findings to suggest an infective etiology; however, this cannot be definitively excluded. | ||
== Eosinophilic esophagitis == | |||
===Microscopic description=== | |||
A. The sections show small bowel with Brunner's glands and a mild focal neutrophilic infiltrate. The villous architecture is largely preserved.<br> | |||
B. The sections show small bowel with Brunner's glands and moderate chronic active neutrophilic inflammation with focal ulceration and necrotic debris. There is villous blunting. There are no significant number of intraepithelial lymphocytes.<br> | |||
C. The sections show antral-type gastric mucosa with infiltration moderate eosinophilia, neutrophils and clusters of plasma cells. Focally, the eosinophils are intraepithelial.<br> | |||
D. The sections show body-type gastric mucosa with clusters of eosinophilis, neutrophils and plasma cells.<br> | |||
E-G. The sections show esophageal mucosa with a prominent eosinophilic infiltrate and focal clustering of eosinophilis. The epithelial papillae are elongated, there is basal cell hyperplasia and the epithelium is edematous. There are more than 20 eosinophilis / 0.216 mm^2 in all sites. The area 0.216 mm^2 is one high power field (HPF) using the 40x objective.<br> | |||
===Final diagnosis=== | |||
A. Duodenum, biopsy - Mild focal duodenitis, see comment.<br> | |||
B. Duodenum, cap, biopsy - Moderate focal chronic active duodenitis with mild eosinophilia and ulceration, see comment.<br> | |||
C. Stomach, antrum, biopsy - Moderate chronic active gastritis with mild eosinophilia.<br> | |||
D. Stomach, body, biopsy - Mild chronic active gastritis with mild eosinophilia.<br> | |||
E. Esophagus, distal, biopsy - Eosinophilic esophagitis.<br> | |||
F. Esophagus, middle, biopsy - Eosinophilic esophagitis.<br> | |||
G. Esophagus, upper, biopsy - Eosinophilic esophagitis.<br> | |||
====Comment==== | |||
The histomorphologic findings in this biopsy are not suggestive of celiac disease. | |||