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==General== | ==General== | ||
*What? | *What? | ||
**Trophoblastic tissue deeper than it should be | **Trophoblastic tissue deeper than it should be, so the placenta fails to separate at time of delivery | ||
*Clinical? | *Clinical? | ||
**Failure of placenta to deliver spontaneously | |||
**Postpartum hemorrhage leading to a hysterectomy.<ref name=pmid18514815>{{Cite journal | last1 = Tantbirojn | first1 = P. | last2 = Crum | first2 = CP. | last3 = Parast | first3 = MM. | title = Pathophysiology of placenta creta: the role of decidua and extravillous trophoblast. | journal = Placenta | volume = 29 | issue = 7 | pages = 639-45 | month = Jul | year = 2008 | doi = 10.1016/j.placenta.2008.04.008 | PMID = 18514815 }}</ref> | **Postpartum hemorrhage leading to a hysterectomy.<ref name=pmid18514815>{{Cite journal | last1 = Tantbirojn | first1 = P. | last2 = Crum | first2 = CP. | last3 = Parast | first3 = MM. | title = Pathophysiology of placenta creta: the role of decidua and extravillous trophoblast. | journal = Placenta | volume = 29 | issue = 7 | pages = 639-45 | month = Jul | year = 2008 | doi = 10.1016/j.placenta.2008.04.008 | PMID = 18514815 }}</ref> | ||
**May be associated with antepartum hemorrhage | |||
**Discovered on ultrasound during pregnancy, especially when associated with placenta previa | |||
*Pathogenesis? | *Pathogenesis? | ||
**It is suspected that it arises as there is defect in the endometrium/myometrium -- ''not'' deep trophoblastic invasion.<ref name=pmid18514815/> | **It is suspected that it arises as there is defect in the endometrium/myometrium -- ''not'' deep trophoblastic invasion.<ref name=pmid18514815/> |
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