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| Micro = nuclear pleomorphism (may be mild), usually glandular differentiation (most common), no urothelial differentiation - '''essential''' | | Micro = nuclear pleomorphism (may be mild), usually glandular differentiation (most common), no urothelial differentiation - '''essential''' | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[urachal carcinoma]], invasive [[urothelial carcinoma]] with glandular differentiation, [[metastatic]] adenocarcinoma (esp. [[colorectal adenocarcinoma]]) | | LMDDx = [[urachal carcinoma]], invasive [[urothelial carcinoma]] with glandular differentiation, [[metastatic]] adenocarcinoma, direct extension of [[adenocarcinoma]] from an adjacent structure (esp. [[colorectal adenocarcinoma]]) | ||
| Stains = | | Stains = | ||
| IHC = CK7 +ve, CK20 +ve, CDX2 +ve (strong, diffuse), beta-catenin +ve (membranous, not nuclear) | | IHC = CK7 +ve, CK20 +ve, CDX2 +ve (strong, diffuse), beta-catenin +ve (membranous, not nuclear) |
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