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Difference between revisions of "Ependymoma"
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Several pictures including tumor subtypes added...
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Jensflorian (talk | contribs) (Several pictures including tumor subtypes added...) |
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = File:Ependymoma_H%26E.jpg | |||
| Width = | |||
| Caption = Ependymoma grade II WHO. [[H&E stain]] | |||
| Synonyms = | |||
| Micro = Perivascular pseudorosettes, ependymal rosettes | |||
| Subtypes = Tanycytic, Clear cell, Papillary, Cellular | |||
| LMDDx = [[Subependymoma]], [[Glioblastoma]], [[Pilocytic astrocytoma]], [[Oligodendroglioma]] | |||
| Stains = | |||
| IHC = GFAP +ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = intermediate to poor (WHO Grades II & III) | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Ependymoma''' is a [[neuropathology tumour]]. | '''Ependymoma''' is a [[neuropathology tumour]]. | ||
''Myxopapillary ependymoma'' is dealt with separately in the [[myxopapillary ependymoma]] article. | * ''Myxopapillary ependymoma'' is dealt with separately in the [[myxopapillary ependymoma]] article. | ||
* ''Subependymoma'' is dealt with separately in the [[Subependymoma]] article. | |||
==General== | ==General== | ||
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<gallery> | <gallery> | ||
File:AFIP405711R-EPENDYMOMA.jpg | Radiology (AFIP) | File:AFIP405711R-EPENDYMOMA.jpg | Radiology (AFIP) | ||
File:AFIP405713G-EPENDYMOMA.jpg | Ependymoma in the fourth ventricle (AFIP) | |||
File:Ependymoma in the fourth ventricle.jpg | Gross (AFIP) | File:Ependymoma in the fourth ventricle.jpg | Gross (AFIP) | ||
</gallery> | </gallery> | ||
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*[[Glioblastoma]] (GBM). | *[[Glioblastoma]] (GBM). | ||
**Invasive border = GBM; circumscribed border of lesion = ependymoma. | **Invasive border = GBM; circumscribed border of lesion = ependymoma. | ||
*[[Pilocytic astrocytoma]] (Tanycytic ependymoma) | |||
*[[Oligodendroglioma]] (Clear cell ependymoma)) | |||
====Images==== | ====Images==== | ||
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*[http://path.upmc.edu/cases/case324.html Anaplastic ependymoma - case 2 (upmc.edu)]. | *[http://path.upmc.edu/cases/case324.html Anaplastic ependymoma - case 2 (upmc.edu)]. | ||
<gallery> | <gallery> | ||
File:AFIP405736M-EPENDYMOMA.jpg | Ependymoma smear. (AFIP) | |||
File:AFIP405715M-EPENDYMOMA.jpg | Perivascular pseudorosettes in a ependymoma. (AFIP) | |||
Image:Ependymoma_intermed_mag.jpg | Ependymoma - intermed. mag. (WC) | Image:Ependymoma_intermed_mag.jpg | Ependymoma - intermed. mag. (WC) | ||
Image:Ependymoma_low_intermed_mag.jpg | Ependymoma - low mag. (WC) | Image:Ependymoma_low_intermed_mag.jpg | Ependymoma - low mag. (WC) | ||
File:Ependymoma_H%26E.jpg | Ependymoma - high mag. (WC/Sbrandner) | |||
File:Ependymoma_true_ependymal_rosettes_and_pseudorosettes.jpg | True ependymal and pseudorosettes in a ependymoma. (WC/jensflorian) | |||
File:Ependymal_linings_ependymoma_HE.jpg | Ependymal linings in a ependymoma. (WC/jensflorian) | |||
File:Ependymoma_GFAP.jpg | GFAP IHC in a ependymoma. (WC/jensflorian) | |||
File:Ependymoma_GFAP.jpg| GFAP IHC in a ependymoma. (WC/Sbrandner) | |||
File:EMA_ependymoma_periluminal.jpg | Periluminal EMA positivity in a ependymoma. (WC/jensflorian) | |||
File:Ependymoma_EMA.jpg | Dot-like EMA immunreactivity n a ependymoma. (WC/Marvin101) | |||
File:Tanycytic ependymoma HE.jpg | Tanycytic ependymoma must not confused with [[pilocytic astrocytoma]]. (WC/jensflorian) | |||
File:Tanicytic_ependymoma_x10.jpg | Tanycytic ependymoma - low mag. (WC/jensflorian) | |||
File:Papillary_Ependymoma.jpg | Papillary ependymoma - low mag. (WC/jensflorian) | |||
File:Papillary_ependymoma_HE_x40.jpg | Papillary ependymoma - intermed. mag. (WC/jensflorian) | |||
File:Clear_cell_ependymoma_HE.jpg | Clear cell ependymoma may mimic [[oligodendroglioma]]. (WC/jensflorian) | |||
File:HE_anaplastic_epedymomas_mitoses_pleomorphism.jpg | Brisk mitotic activity in a anaplastic ependymoma. (WC/jensflorian) | |||
</gallery> | </gallery> | ||
===Grading=== | ===Grading=== | ||