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- MARGINS CLEAR OF ADENOMA (NEAREST MARGIN 1.0 CM). | - MARGINS CLEAR OF ADENOMA (NEAREST MARGIN 1.0 CM). | ||
</pre> | </pre> | ||
==Intracystic Papillary Neoplasm of the Gallbladder<ref>{{Cite journal | last1 = Adsay | first1 = V. | last2 = Jang | first2 = KT. | last3 = Roa | first3 = JC. | last4 = Dursun | first4 = N. | last5 = Ohike | first5 = N. | last6 = Bagci | first6 = P. | last7 = Basturk | first7 = O. | last8 = Bandyopadhyay | first8 = S. | last9 = Cheng | first9 = JD. | title = Intracholecystic papillary-tubular neoplasms (ICPN) of the gallbladder (neoplastic polyps, adenomas, and papillary neoplasms that are ≥1.0 cm): clinicopathologic and immunohistochemical analysis of 123 cases. | journal = Am J Surg Pathol | volume = 36 | issue = 9 | pages = 1279-301 | month = Sep | year = 2012 | doi = 10.1097/PAS.0b013e318262787c | PMID = 22895264 }} | |||
</ref>== | |||
===General=== | |||
*Low-grade lesions previously designated “papillary adenoma” | |||
*High-grade lesions previously designated “noninvasive papillary carcinoma.” | |||
*Oten arise in a background of pyloric-gland metaplasia. | |||
*May be associated with invasive adenocarcinoma, which should be reported as intracystic papillary neoplasm with an associated invasive carcinoma and staged. | |||
===Microscopic=== | |||
*Cell types | |||
**Pancreatobiliary type | |||
**Intestinal phenotypes with goblet, Paneth, and/or serotonin-containing cells. | |||
*Architecture | |||
**Papillary | |||
**Tubulopapillary | |||
**Tubular | |||
=Malignant= | =Malignant= |
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