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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Pseudohyperplastic carcinoma -- high mag.jpg | |||
| Width = | |||
| Caption = Pseudohyperplastic carcinoma. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = medium to large glands with an atypical morphology (papillary or pseudopapillary infoldings, luminal undulations, branching or cystic dilatation), nuclear features of conventional prostate cancer (nucleoli, nuclear enlargement) | |||
| Subtypes = subtype of [[prostate carcinoma]] | |||
| LMDDx = benign prostatic tissue, [[foamy gland carcinoma]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = [[prostate biopsy]], [[prostate chips]], [[radical prostatectomy]] | |||
| Staging = [[prostate cancer staging]] | |||
| Site = [[prostate gland]] - see ''[[prostate carcinoma]]'' | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = +/-[[PSA]] elevated | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = | |||
| Tx = see ''[[prostate carcinoma]]'' | |||
}} | |||
'''Pseudohyperplastic prostatic adenocarcinoma''', also '''pseudohyperplastic adenocarcinoma''' is an uncommon type of [[prostate carcinoma]] that may mimic benign [[prostate gland|prostate]]. | '''Pseudohyperplastic prostatic adenocarcinoma''', also '''pseudohyperplastic adenocarcinoma''' is an uncommon type of [[prostate carcinoma]] that may mimic benign [[prostate gland|prostate]]. | ||
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**Papillary or pseudopapillary infoldings, luminal undulations, branching or cystic dilatation. | **Papillary or pseudopapillary infoldings, luminal undulations, branching or cystic dilatation. | ||
*Nuclear features of conventional prostate cancer (nucleoli, nuclear enlargement). | *Nuclear features of conventional prostate cancer (nucleoli, nuclear enlargement). | ||
Notes: | |||
*Often associated with conventional (acinar) prostate adenocarcinoma. | |||
*Pale abundant cytoplasm - similar to normal prostate. | |||
DDx: | DDx: | ||
*[[Foamy gland carcinoma]] - often lack prominent nucleoli, smaller glands. | *[[Foamy gland carcinoma]] - often lack prominent nucleoli, smaller glands. | ||
*Benign prostatic glands. | *Benign prostatic glands - esp. at low power. | ||
===Images=== | ===Images=== | ||
<gallery> | |||
Image: Pseudohyperplastic carcinoma -- low mag.jpg | PHC - low mag. | |||
Image: Pseudohyperplastic carcinoma -- intermed mag.jpg | PHC - intermed. mag. | |||
Image: Pseudohyperplastic carcinoma -- high mag.jpg | PHC - high mag. | |||
Image: Pseudohyperplastic carcinoma - alt -- intermed mag.jpg | PHC - intermed. mag. | |||
Image: Pseudohyperplastic carcinoma - alt -- high mag.jpg | PHC - high mag. | |||
</gallery> | |||
www: | |||
*[http://www.webpathology.com/image.asp?n=29&Case=23 Pseudohyperplastic adenocarcinoma (webpathology.com)]. | *[http://www.webpathology.com/image.asp?n=29&Case=23 Pseudohyperplastic adenocarcinoma (webpathology.com)]. | ||
*[http://www.nature.com/modpathol/journal/v17/n3/fig_tab/3800050f13.html Pseudohyperplastic prostatic adenocarcinoma (nature.com)]. | *[http://www.nature.com/modpathol/journal/v17/n3/fig_tab/3800050f13.html Pseudohyperplastic prostatic adenocarcinoma (nature.com)]. | ||
==See also== | ==See also== |
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