Difference between revisions of "Intraductal carcinoma of the prostate"

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'''Intraductal carcinoma of the prostate''', abbreviated '''IDCP''', is a proliferation of [[malignant]] [[prostate gland|prostate]] cells within glands that have an intact basal cell layer.
'''Intraductal carcinoma of the prostate''', abbreviated '''IDCP''', is a proliferation of [[malignant]] [[prostate gland|prostate]] cells within glands that have an intact basal cell layer.


==General==
==General==
*May represent a precursor to invasive [[prostate carcinoma]].<ref name=pmid24966964>{{Cite journal  | last1 = Miyai | first1 = K. | last2 = Divatia | first2 = MK. | last3 = Shen | first3 = SS. | last4 = Miles | first4 = BJ. | last5 = Ayala | first5 = AG. | last6 = Ro | first6 = JY. | title = Heterogeneous clinicopathological features of intraductal carcinoma of the prostate: a comparison between "precursor-like" and "regular type" lesions. | journal = Int J Clin Exp Pathol | volume = 7 | issue = 5 | pages = 2518-26 | month =  | year = 2014 | doi =  | PMID = 24966964 }}</ref>
*Associated with a poor prognosis.<ref name=pmid19246509>{{Cite journal  | last1 = Henry | first1 = PC. | last2 = Evans | first2 = AJ. | title = Intraductal carcinoma of the prostate: a distinct histopathological entity with important prognostic implications. | journal = J Clin Pathol | volume = 62 | issue = 7 | pages = 579-83 | month = Jul | year = 2009 | doi = 10.1136/jcp.2009.065003 | PMID = 19246509 }}</ref>
*Associated with a poor prognosis.<ref name=pmid19246509>{{Cite journal  | last1 = Henry | first1 = PC. | last2 = Evans | first2 = AJ. | title = Intraductal carcinoma of the prostate: a distinct histopathological entity with important prognostic implications. | journal = J Clin Pathol | volume = 62 | issue = 7 | pages = 579-83 | month = Jul | year = 2009 | doi = 10.1136/jcp.2009.065003 | PMID = 19246509 }}</ref>
*Strong association with aggressive invasive carcinomas on prostatectomy when identified in isolation on biopsy.<ref name=pmid20723921>{{Cite journal  | last1 = Robinson | first1 = BD. | last2 = Epstein | first2 = JI. | title = Intraductal carcinoma of the prostate without invasive carcinoma on needle biopsy: emphasis on radical prostatectomy findings. | journal = J Urol | volume = 184 | issue = 4 | pages = 1328-33 | month = Oct | year = 2010 | doi = 10.1016/j.juro.2010.06.017 | PMID = 20723921 }}</ref>
*Strong association with aggressive invasive carcinomas on prostatectomy when identified in isolation on biopsy.<ref name=pmid20723921>{{Cite journal  | last1 = Robinson | first1 = BD. | last2 = Epstein | first2 = JI. | title = Intraductal carcinoma of the prostate without invasive carcinoma on needle biopsy: emphasis on radical prostatectomy findings. | journal = J Urol | volume = 184 | issue = 4 | pages = 1328-33 | month = Oct | year = 2010 | doi = 10.1016/j.juro.2010.06.017 | PMID = 20723921 }}</ref>
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