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=====Microscopic===== | =====Microscopic===== | ||
Features: | Features: | ||
* | *Circumscribed or even encapsulated neoplasm. | ||
*Morules - balls of | *Morules - interspersed balls of squamoid cells | ||
**no keritinization or intercellular bridges. | |||
**Homogenous, lightly eosinophilic glassy nuclei | |||
. | |||
*Follicles | |||
**Cribriform, papillary, trabecular and solid patterns. | |||
**Columnar or cuboidal cells. | |||
**Little colloid | |||
**Papillary carcinoma nuclear features. | |||
DDX: | |||
*Papillary thyroid carcinoma | |||
*Papillary thyroid carcinoma, tall cell variant | |||
<gallery> | |||
Image:Thyroid PapillaryCarcinoma CribriformMorularVariant MP3 13BR***.jpg|Thyroid - Papillary Carcinoma Cribriform Morular Variant - Medium power (SKB) | |||
Image:Thyroid PapillaryCarcinoma CribriformMorularVariant HP2 13BR***.jpg|Thyroid - Papillary Carcinoma Cribriform Morular Variant - High power (SKB) | |||
Image:Thyroid PapillaryCarcinoma CribriformMorularVariant HP3 13BR***.jpg|Thyroid - Papillary Carcinoma Cribriform Morular Variant - high power]] | |||
Image:Thyroid PapillaryCarcinoma CribriformMorularVariant CDX2 HP 13BR***.jpg|Thyroid - Papillary Carcinoma Cribriform Morular Variant - CDX2 (SKB) | |||
Image:Thyroid PapillaryCarcinoma CribriformMorularVariant P16 HP 13BR***.jpg|Thyroid - Papillary Carcinoma Cribriform Morular Variant - p16 (SKB) | |||
Image:Thyroid PapillaryCarcinoma CribriformMorularVariant P16 HP3 13BR***.jpg|Thyroid - Papillary Carcinoma Cribriform Morular Variant - p16 (SKB) | |||
Image:Thyroid PapillaryCarcinoma CribriformMorularVariant ER HP 13BR***.jpg|Thyroid - Papillary Carcinoma Cribriform Morular Variant - ER (SKB) | |||
Image:Thyroid PapillaryCarcinoma CribriformMorularVariant betaCatenin HP 13BR***.jpg|Thyroid - Papillary Carcinoma Cribriform Morular Variant - beta catenin (SKB) | |||
</gallery> | |||
====Papillary thyroid carcinoma diffuse sclerosing variant==== | ====Papillary thyroid carcinoma diffuse sclerosing variant==== |
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