Difference between revisions of "Sertoli-Leydig cell tumour"

Sertoli-Leydig cell tumour (view source)

20 bytes added , 10:41, 21 March 2015

653

edits

@@ Line 51: / Line 51: @@
 *Vimentin +ve.<ref name=pmid20349790>{{Cite journal  | last1 = Kondi-Pafiti | first1 = A. | last2 = Grapsa | first2 = D. | last3 = Kairi-Vassilatou | first3 = E. | last4 = Carvounis | first4 = E. | last5 = Hasiakos | first5 = D. | last6 = Kontogianni | first6 = K. | last7 = Fotiou | first7 = S. | title = Granulosa cell tumors of the ovary: a clinicopathologic and immunohistochemical study of 21 cases. | journal = Eur J Gynaecol Oncol | volume = 31 | issue = 1 | pages = 94-8 | month =  | year = 2010 | doi =  | PMID = 20349790 }}</ref>
 *CD99 +ve.
-*AE1/AE3 and PanKeratin can be +ve
+*AE1/AE3 and PanKeratin +ve
 Others:<ref name=pmid20349790/>
@@ Line 57: / Line 57: @@
 *'''EMA''' -ve.
-Pan-keratins and AE1/AE3 may mark granulosa cell tumors and Sertoli cell tumors causing confusion with adenocarcinoma. EMA is a better marker to exclude an epithelial tumor as EMA is negative in sex cord-stromal tumors.  Adding complexity, endometrioid adenocarcinomas may occasionally weakly express inhibin, calretinin or WT-1.
+Pan-keratins and AE1/AE3 may mark granulosa cell tumors and Sertoli cell tumors causing confusion with adenocarcinoma. EMA is a better marker to exclude an epithelial tumor as EMA is negative in sex cord-stromal tumors.  Highlighting why a panel of stains is needed, endometrioid adenocarcinomas may occasionally weakly express inhibin, calretinin or WT-1.
 ==See also==