Difference between revisions of "Thyroid gland"

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224 bytes added ,  02:59, 18 January 2011
(→‎Weird stuff: oncocytic)
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**C cells (AKA ''parafollicular cell''): abundant cytoplasm - clear/pale.
**C cells (AKA ''parafollicular cell''): abundant cytoplasm - clear/pale.


IHC:<ref>[http://pathologyoutlines.com/thyroid.html#medullary http://pathologyoutlines.com/thyroid.html#medullary]</ref>
Images:
*[http://jcp.bmj.com/content/vol57/issue3/images/large/cp8474.f16.jpeg Medullary thyroid carcinoma (bmj.com)].
*[http://www.nature.com/ki/journal/v70/n11/fig_tab/5001888f2.html C cell hyperplasia (nature.com)].
*[http://lifesci.rutgers.edu/~babiarz/Review3/Lp6/scope8.htm C cell (rutgers.edu)].
*[http://www.anatomyatlases.org/MicroscopicAnatomy/Images/Plate287.jpg Parafollicular cells (anatomyatlases.org)].
 
===IHC===
Features:<ref>URL: [http://pathologyoutlines.com/thyroid.html#medullary http://pathologyoutlines.com/thyroid.html#medullary]. Accessed on: 17 January 2011.</ref>
*[[Calcitonin]] +ve - it arises from C cells (which produce calcitonin).
*[[Calcitonin]] +ve - it arises from C cells (which produce calcitonin).
*Congo-red +ve (amyloid present) - mnemonic: ''CRAP'' -- congo red amyloid protein.
*Congo-red +ve (amyloid present) - mnemonic: ''CRAP'' -- congo red amyloid protein.
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*CEA +ve (often better staining than calcitonin).<ref>SB. 7 January 2010.</ref>
*CEA +ve (often better staining than calcitonin).<ref>SB. 7 January 2010.</ref>


Image:
===EM===
*[http://jcp.bmj.com/content/vol57/issue3/images/large/cp8474.f16.jpeg Medullary thyroid carcinoma (bmj.com)].
*Neurosecretory granules.
*[http://www.nature.com/ki/journal/v70/n11/fig_tab/5001888f2.html C cell hyperplasia (nature.com)].
**Feature seen in neuroendocrine tumours.
*[http://lifesci.rutgers.edu/~babiarz/Review3/Lp6/scope8.htm C cell (rutgers.edu)].
 
*[http://www.anatomyatlases.org/MicroscopicAnatomy/Images/Plate287.jpg Parafollicular cells (anatomyatlases.org)].
Images: [http://pathhsw5m54.ucsf.edu/case7/image77.html Neurosecretory granules (ucsf.edu)].


==Anaplastic thyroid carcinoma==
==Anaplastic thyroid carcinoma==
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