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Difference between revisions of "Neurofibroma"
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→Microscopic
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Features: | Features: | ||
*Spindle cells with wavy nuclei without pleomorphism - '''key feature'''. | *Spindle cells with wavy nuclei without pleomorphism - '''key feature'''. | ||
* | *Intermixed with wire-like collagen. | ||
**Often no pattern is apparent. | **Often no pattern is apparent. | ||
**Often described as "shredded carrots".<ref name=pmid24216989>{{Cite journal | last1 = Bernthal | first1 = NM. | last2 = Jones | first2 = KB. | last3 = Monument | first3 = MJ. | last4 = Liu | first4 = T. | last5 = Viskochil | first5 = D. | last6 = Randall | first6 = RL. | title = Lost in translation: ambiguity in nerve sheath tumor nomenclature and its resultant treatment effect. | journal = Cancers (Basel) | volume = 5 | issue = 2 | pages = 519-28 | month = | year = 2013 | doi = 10.3390/cancers5020519 | PMID = 24216989 }}</ref> | |||
*Moderate increase of cellularity vis-a-vis normal dermis. | *Moderate increase of cellularity vis-a-vis normal dermis. | ||
*May be poorly or well-circumscribed. | *May be poorly or well-circumscribed. | ||