Difference between revisions of "Salivary glands"

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Salivary glands (view source)

Revision as of 17:38, 18 March 2015

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==Myoepithelioma==
==Myoepithelioma==
===General===
{{Main|Myoepithelioma}}
*Usually benign.
**May be malignant.
 
Location - head and neck:<ref name=pmid2982059>{{Cite journal  | last1 = Barnes | first1 = L. | last2 = Appel | first2 = BN. | last3 = Perez | first3 = H. | last4 = El-Attar | first4 = AM. | title = Myoepithelioma of the head and neck: case report and review. | journal = J Surg Oncol | volume = 28 | issue = 1 | pages = 21-8 | month = Jan | year = 1985 | doi =  | PMID = 2982059 }}</ref>
*Parotid gland ~50%.
*Palate ~25%
*Submandibular gland ~12%.
 
Notes:
*First described in 1972.<ref name=pmid5075358>{{Cite journal  | last1 = Saksela | first1 = E. | last2 = Tarkkanen | first2 = J. | last3 = Wartiovaara | first3 = J. | title = Parotid clear-cell adenoma of possible myoepithelial origin. | journal = Cancer | volume = 30 | issue = 3 | pages = 742-8 | month = Sep | year = 1972 | doi =  | PMID = 5075358 }}</ref>
*May be seen in the skin.<ref name=pmid11224605>{{Cite journal  | last1 = Kutzner | first1 = H. | last2 = Mentzel | first2 = T. | last3 = Kaddu | first3 = S. | last4 = Soares | first4 = LM. | last5 = Sangueza | first5 = OP. | last6 = Requena | first6 = L. | title = Cutaneous myoepithelioma: an under-recognized cutaneous neoplasm composed of myoepithelial cells. | journal = Am J Surg Pathol | volume = 25 | issue = 3 | pages = 348-55 | month = Mar | year = 2001 | doi =  | PMID = 11224605 }}</ref>
===Microsopic===
Features:<ref name=Ref_DCHH130>{{Ref DCHH|130}}</ref>
*Myoepithelial cells - may be:
**Spindled.
**Plasmacytoid.
**Epithelioid.
**Clear (rare).
*Lack tubules, i.e. epithelial component.
**May be up to 10% (or 5%<ref>I. Weinreb. 24 October 2011.</ref>).
 
DDx:
*[[Pleomorphic adenoma]].
 
====Images====
<gallery>
Image: Myoepithelioma - low mag.jpg | Myoepithelioma - low mag. (WC/Nephron)
Image: Myoepithelioma_-_intermed_mag.jpg | Myoepithelioma - intermed. mag. (WC/Nephron)
Image: Myoepithelioma - high mag.jpg | Myoepithelioma - high mag. (WC/Nephron)
Image: Myoepithelioma_-_very_high_mag.jpg | Myoepithelioma - very high mag. (WC/Nephron)
</gallery>
 
===IHC===
Features:<ref name=Ref_DCHH130>{{Ref DCHH|130}}</ref>
*S100 +ve.
*GFAP +ve.
*CK14 +ve.
 
Others:<ref name=Ref_DCHH18>{{Ref DCHH|18}}</ref>
*SMA +ve.
*Calponin +ve.


==Basal cell adenoma==
==Basal cell adenoma==
Michael
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