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Difference between revisions of "Extranodal NK/T-cell lymphoma, nasal type"
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Extranodal NK/T-cell lymphoma, nasal type (view source)
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'''Extranodal NK/T-cell lymphoma, nasal_type''', also known as '''extranodal natural kill lymphoma''' and '''angiocentric lymphoma''', is a rare type of [[lymphoma]]. | |||
==General== | |||
*Common in east Asia.<ref name=pmid18283711>{{Cite journal | last1 = Suzuki | first1 = R. | last2 = Takeuchi | first2 = K. | last3 = Ohshima | first3 = K. | last4 = Nakamura | first4 = S. | title = Extranodal NK/T-cell lymphoma: diagnosis and treatment cues. | journal = Hematol Oncol | volume = 26 | issue = 2 | pages = 66-72 | month = Jun | year = 2008 | doi = 10.1002/hon.847 | PMID = 18283711 }}</ref> | |||
*Strong association with [[EBV]]. | |||
==Microscopic== | |||
Features: | |||
*Atypical lymphoid cells: | |||
**[[Nucleoli]]. | |||
**[[Nuclear pleomorphism]]. | |||
**Cells centered around vessels (angiocentric). | |||
***May destroy small and medium sized arterioles. | |||
Images: | |||
*[http://path.upmc.edu/cases/case231/micro.html Extranodal NK/T-cell lymphoma, nasal type - case 1 - several images (upmc.edu)]. | |||
*[http://path.upmc.edu/cases/case310.html Extranodal NK/T-cell lymphoma, nasal type - case 2 - several images (upmc.edu)]. | |||
==IHC== | |||
Features:<ref name=pmid17064952>{{Cite journal | last1 = Al-Hakeem | first1 = DA. | last2 = Fedele | first2 = S. | last3 = Carlos | first3 = R. | last4 = Porter | first4 = S. | title = Extranodal NK/T-cell lymphoma, nasal type. | journal = Oral Oncol | volume = 43 | issue = 1 | pages = 4-14 | month = Jan | year = 2007 | doi = 10.1016/j.oraloncology.2006.03.011 | PMID = 17064952 }}</ref> | |||
*CD2 +ve. | |||
*CD3 +ve (cytoplasmic). | |||
*[[CD56]] +ve. | |||
Others:<ref>URL: [http://path.upmc.edu/cases/case310.html http://path.upmc.edu/cases/case310.html]. Accessed on: 14 January 2012.</ref> | |||
*TIA-1 +ve. | |||
*CD7 +ve. | |||
*EBER +ve. | |||
==See also== | |||
*[[Lymphoma]]. | |||
==References== | |||
{{References|1}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||