653
edits
Line 44: | Line 44: | ||
**The controversy centres on whether to call all mucinous tumours outside of the appendix ''adenocarcinoma'' - regardless of whether they have [[nuclear atypia|atypia]] & show invasion. | **The controversy centres on whether to call all mucinous tumours outside of the appendix ''adenocarcinoma'' - regardless of whether they have [[nuclear atypia|atypia]] & show invasion. | ||
*Many potential pathways for extraappendiceal spread and peritoneal mucin deposition (pseudomyxoma peritonei) | *Many potential pathways for extraappendiceal spread and peritoneal mucin deposition (pseudomyxoma peritonei) | ||
**A | **A mucinous neoplasm ruptures the appendix due to expansion by excessive mucin | ||
**Malignant mucinous glands infiltrate through the appendiceal wall and spread throughout the peritoneum. | ***Could occur with either a benign or malignant neoplam. | ||
** | **Malignant mucinous glands infiltrate through the appendiceal wall or enter the lymphatics and spread throughout the peritoneum. | ||
***Would require a malignant neoplasm. | |||
*''Panarelli and Yantiss'' created a nice summary table - that compares the classifications - see: [http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-135-10-1261-t01&doi=10.5858%2Farpa.2011-0034-RA comparison of classifications (archivesofpathology.org)].<ref name=pmid21970481/> | *''Panarelli and Yantiss'' created a nice summary table - that compares the classifications - see: [http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-135-10-1261-t01&doi=10.5858%2Farpa.2011-0034-RA comparison of classifications (archivesofpathology.org)].<ref name=pmid21970481/> | ||
*In women - an ovarian primary must be excluded. | *In women - an ovarian primary must be excluded. |
edits