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Difference between revisions of "Thyroid gland nodular hyperplasia"
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Thyroid gland nodular hyperplasia (view source)
Revision as of 05:57, 4 March 2015
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**If you've seen a handful of thyroids you've seen this. | **If you've seen a handful of thyroids you've seen this. | ||
*Considered to be a combination of environmental factors (e.g. lack of iodine in the diet) and genetic factors (often with autosomal dominant inheritance).<ref name=pmid21487943>{{Cite journal | last1 = Paschke | first1 = R. | title = Molecular pathogenesis of nodular goiter. | journal = Langenbecks Arch Surg | volume = 396 | issue = 8 | pages = 1127-36 | month = Dec | year = 2011 | doi = 10.1007/s00423-011-0788-5 | PMID = 21487943 }}</ref> | *Considered to be a combination of environmental factors (e.g. lack of iodine in the diet) and genetic factors (often with autosomal dominant inheritance).<ref name=pmid21487943>{{Cite journal | last1 = Paschke | first1 = R. | title = Molecular pathogenesis of nodular goiter. | journal = Langenbecks Arch Surg | volume = 396 | issue = 8 | pages = 1127-36 | month = Dec | year = 2011 | doi = 10.1007/s00423-011-0788-5 | PMID = 21487943 }}</ref> | ||
==Gross== | ==Gross== | ||
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Image: Thyroid FNA, Benign, Consistent with Adenomatoid Nodule (8116075837).jpg | FNA c/w AN. (WC/Euthman) | Image: Thyroid FNA, Benign, Consistent with Adenomatoid Nodule (8116075837).jpg | FNA c/w AN. (WC/Euthman) | ||
</gallery> | </gallery> | ||
==Molecular== | |||
*Large lesions may be clonal;<ref name=pmid1973172>{{Cite journal | last1 = Namba | first1 = H. | last2 = Matsuo | first2 = K. | last3 = Fagin | first3 = JA. | title = Clonal composition of benign and malignant human thyroid tumors. | journal = J Clin Invest | volume = 86 | issue = 1 | pages = 120-5 | month = Jul | year = 1990 | doi = 10.1172/JCI114673 | PMID = 1973172 }}</ref> however, this is not used for diagnosis and considered clinically irrelevant. | |||
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