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'''Follicular thyroid carcinoma''', abbreviated '''FTC''', is an uncommon malignancy of the [[thyroid gland]]. It is also known as ''follicular carcinoma''. | |||
==General== | |||
===Clinical=== | |||
Medical school memory device ''4 Fs'': | |||
*FNA NOT diagnosable. | |||
*Far away mets (sometimes). | |||
*Female predominant. | |||
*Favourable prognosis. | |||
Notes: | |||
*Usu. has a hematologic spread. | |||
**PTC usu. spread via lymphatics. | |||
==Microscopic== | |||
Features: | |||
*Defined by either: | |||
*#Invasion through the capsule: | |||
*#*Should be all the way through.<ref>SR. 17 January 2011.</ref> | |||
*#**1/2 does not count. | |||
*#**Fibrous reaction does not count. | |||
*#**"Above the contour" does not count. | |||
*#Vascular invasion (all of the following): | |||
*##In a small vein (not a capillary), that is outside of the tumour mass. | |||
*##Tumour adherent to the side of the vessel. | |||
*##Tumour must be re-endothelialized. | |||
Notes: | |||
*'''Impossible''' to differentiate from ''[[follicular thyroid adenoma|follicular adenoma]]'' on FNA (no cytologic differences). | |||
*Described as "over-diagnosed" ... misdiagnoses: PTC follicular variant, follicular adenoma, multinodular goitre with a thick capsule. | |||
===Images=== | |||
www: | |||
*[http://path.upmc.edu/cases/case653.html Follicular thyroid carcinoma - several images (upmc.edu)]. | |||
==See also== | |||
*[[Thyroid gland]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Thyroid gland]] |
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