|
|
Line 400: |
Line 400: |
| ==Follicular thyroid carcinoma== | | ==Follicular thyroid carcinoma== |
| *[[AKA]] ''follicular carcinoma''. | | *[[AKA]] ''follicular carcinoma''. |
| ===Clinical===
| | {{Main|Follicular thyroid carcinoma}} |
| Medical school memory device ''4 Fs'':
| |
| *FNA NOT diagnosable.
| |
| *Far away mets (sometimes).
| |
| *Female predominant.
| |
| *Favourable prognosis.
| |
| | |
| Notes:
| |
| *Usu. has a hematologic spread.
| |
| **PTC usu. spread via lymphatics.
| |
| | |
| ===Microscopic===
| |
| Features:
| |
| *Defined by either:
| |
| *#Invasion through the capsule:
| |
| *#*Should be all the way through.<ref>SR. 17 January 2011.</ref>
| |
| *#**1/2 does not count.
| |
| *#**Fibrous reaction does not count.
| |
| *#**"Above the contour" does not count.
| |
| *#Vascular invasion (all of the following):
| |
| *##In a small vein (not a capillary), that is outside of the tumour mass.
| |
| *##Tumour adherent to the side of the vessel.
| |
| *##Tumour must be re-endothelialized.
| |
| | |
| Notes:
| |
| *'''Impossible''' to differentiate from ''[[follicular thyroid adenoma|follicular adenoma]]'' on FNA (no cytologic differences).
| |
| *Described as "over-diagnosed" ... misdiagnoses: PTC follicular variant, follicular adenoma, multinodular goitre with a thick capsule.
| |
| | |
| Images:
| |
| *[http://path.upmc.edu/cases/case653.html Follicular thyroid carcinoma - several images (upmc.edu)].
| |
|
| |
|
| ==Medullary thyroid carcinoma== | | ==Medullary thyroid carcinoma== |