Difference between revisions of "Thyroid gland"

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Thyroid gland (view source)

Revision as of 03:25, 4 March 2015

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→‎Follicular thyroid adenoma: split out
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==Follicular thyroid adenoma==
==Follicular thyroid adenoma==
*[[AKA]] follicular adenoma, [[AKA]] thyroid follicular adenoma.
*[[AKA]] follicular adenoma, [[AKA]] thyroid follicular adenoma.
===General===
{{Main|Follicular thyroid adenoma}}
*Most common neoplasm of thyroid.<ref name=Ref_EP51>{{Ref EP|51}}</ref>
*Encapusled lesion (surrounded by fibrous capsule).
 
===Gross===
*Thick capsule.
 
Notes:
*The entire capsule should be submitted.<ref>SR. 17 January 2011.</ref>
**A good start for most thyroid specimens with a thick capsule is 10 blocks.
 
===Microsopic===
Features:
*Cellular.
*Thick capsule - '''key feature'''.
 
Negatives.
*No invasion of the capsule (see ''[[follicular thyroid carcinoma]]'' section).
*No nuclear features suggestive of [[papillary thyroid carcinoma]].
 
DDx:
*[[Thyroid gland nodular hyperplasia]] with an encapsulated nodule - not as cellular.
 
===Sign out===
<pre>
LEFT THYROID, SUPERIOR POLE, EXCISION:
- FOLLICULAR ADENOMA, MAXIMAL DIMENSION 5 MM.
- LYMPHOCYTIC THYROIDITIS.
- NODULAR HYPERPLASIA.
- NEGATIVE FOR MALIGNANCY.
</pre>
 
====Micro====
The section shows a well-circumscribed lesion encapsulated by a thick fibrous capsule (~0.4 mm thick).
 
The lesions consists of microfollicles with a dense appearing colloid. The nuclei have round regular nuclear membranes.  Small indistinct nucleoli are seen at high power.
 
Focally, the lesional cells overlap. However, the chromatin is not cleared. Nuclear grooves are not readily apparent and nuclear pseudoinclusions are not readily identified.


==Graves disease==
==Graves disease==
Michael
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