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Difference between revisions of "Endolymphatic sac tumour"
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==General== | ==General== | ||
*Rare. | *Rare. | ||
*Locally aggressive.<ref name=pmid24966979>{{Cite journal | last1 = Künzel | first1 = J. | last2 = Agaimy | first2 = A. | last3 = Hornung | first3 = J. | last4 = Lell | first4 = M. | last5 = Ganslandt | first5 = O. | last6 = Semrau | first6 = S. | last7 = Zenk | first7 = J. | title = Sporadic endolymphatic sac tumor--a diagnostic and therapeutic challenge. | journal = Int J Clin Exp Pathol | volume = 7 | issue = 5 | pages = 2641-6 | month = | year = 2014 | doi = | PMID = 24966979 }}</ref> | |||
*Associated with [[von Hippel-Lindau disease]]. | |||
==Microscopic== | ==Microscopic== | ||
Features:<ref name=pmid24966979/> | |||
*Cystic spaces. | |||
*Papillary structures. | |||
*Low grade cytomorphology (lack [[nuclear pleomorphism]]). | |||
===Images=== | ===Images=== | ||
www: | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069932/figure/fig02/ ELST (nih.gov)].<ref name=pmid24966975>{{Cite journal | last1 = Yang | first1 = X. | last2 = Liu | first2 = XS. | last3 = Fang | first3 = Y. | last4 = Zhang | first4 = XH. | last5 = Zhang | first5 = YK. | title = Endolymphatic sac tumor with von Hippel-Lindau disease: report of a case with atypical pathology of endolymphatic sac tumor. | journal = Int J Clin Exp Pathol | volume = 7 | issue = 5 | pages = 2609-14 | month = | year = 2014 | doi = | PMID = 24966975 }}</ref> | *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069932/figure/fig02/ ELST (nih.gov)].<ref name=pmid24966975>{{Cite journal | last1 = Yang | first1 = X. | last2 = Liu | first2 = XS. | last3 = Fang | first3 = Y. | last4 = Zhang | first4 = XH. | last5 = Zhang | first5 = YK. | title = Endolymphatic sac tumor with von Hippel-Lindau disease: report of a case with atypical pathology of endolymphatic sac tumor. | journal = Int J Clin Exp Pathol | volume = 7 | issue = 5 | pages = 2609-14 | month = | year = 2014 | doi = | PMID = 24966975 }}</ref> | ||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069893/figure/fig03/ ELST (nih.gov)].<ref name=pmid24966979>{{Cite journal | last1 = Künzel | first1 = J. | last2 = Agaimy | first2 = A. | last3 = Hornung | first3 = J. | last4 = Lell | first4 = M. | last5 = Ganslandt | first5 = O. | last6 = Semrau | first6 = S. | last7 = Zenk | first7 = J. | title = Sporadic endolymphatic sac tumor--a diagnostic and therapeutic challenge. | journal = Int J Clin Exp Pathol | volume = 7 | issue = 5 | pages = 2641-6 | month = | year = 2014 | doi = | PMID = 24966979 | PMC = 4069893}}</ref> | |||
==IHC== | |||
*CD31 +ve - mark the outline of the papillary structures.<ref name=pmid24966979/> | |||
==See also== | ==See also== | ||