48,830
edits
Difference between revisions of "Hypertrophic decidual vasculopathy"
Jump to navigation
Jump to search
Hypertrophic decidual vasculopathy (view source)
Revision as of 07:13, 13 February 2015
, 07:13, 13 February 2015split out
(+cat.) |
(split out) |
||
| Line 1: | Line 1: | ||
# | '''Hypertrophic decidual vasculopathy''', also known as '''decidual vasculopathy''', is a pathology of the placenta seen in the context of (gestational) [[hypertension]]. | ||
==General== | |||
*A change seen in [[hypertension]]. | |||
*Seen in [[intrauterine growth restriction]] (IUGR). | |||
==Microscopic== | |||
Features:<ref name=pmid18641412>{{Cite journal | last1 = Roberts | first1 = DJ. | last2 = Post | first2 = MD. | title = The placenta in pre-eclampsia and intrauterine growth restriction. | journal = J Clin Pathol | volume = 61 | issue = 12 | pages = 1254-60 | month = Dec | year = 2008 | doi = 10.1136/jcp.2008.055236 | PMID = 18641412 }}</ref> | |||
*Mild or moderate: | |||
*#Perivascular inflammatory cells. | |||
*#+/-Vascular [[thrombosis]]. | |||
*#Smooth muscle hypertrophy. | |||
*#Endothelial hyperplasia. | |||
*#*Above two lead to narrowing of the decidual spiral arteries<ref>AFIP - Placental Pathology. P.122. ISBN: 1-881041-89-1. 2004.</ref> -- '''key feature'''. | |||
*Severe:<ref name=pmid18641412/> | |||
*#Atherosis of maternal blood vessels. | |||
*#*Foamy macrophages within vascular wall. | |||
*#[[Fibrinoid necrosis]] of vessel wall (amorphous eosinophilic material vessel wall). | |||
*Suggestive:<ref>{{Ref Placenta|339}}</ref> | |||
**Decidual vasculitis - lymphocyte predominant without plasma cells. | |||
Note: | |||
*''Smooth muscle hypertrophy'' can also be understood as ''lack of physiological conversion of spiral arteries of the uterus''.<ref name=pmid12848643>{{Cite journal | last1 = Naicker | first1 = T. | last2 = Khedun | first2 = SM. | last3 = Moodley | first3 = J. | last4 = Pijnenborg | first4 = R. | title = Quantitative analysis of trophoblast invasion in preeclampsia. | journal = Acta Obstet Gynecol Scand | volume = 82 | issue = 8 | pages = 722-9 | month = Aug | year = 2003 | doi = | PMID = 12848643 }}</ref> | |||
===Images=== | |||
<gallery> | |||
Image:Hypertrophic_decidual_vasculopathy_intermed_mag.jpg | HDV - intermed. mag. (WC) | |||
Image:Hypertrophic_decidual_vasculopathy_low_mag.jpg | HDV - low mag. (WC) | |||
</gallery> | |||
www: | |||
*[http://path.upmc.edu/cases/case75/images/micro2.jpg Atherosis (upmc.edu)].<ref>URL: [http://path.upmc.edu/cases/case75.html http://path.upmc.edu/cases/case75.html]. Accessed on: 2 January 2012.</ref> | |||
*[http://www.surgpath4u.com/caseviewer.php?case_no=490 Decidual vasculopathy (surgpath4u.com)]. | |||
*[http://www.brown.edu/Courses/Digital_Path/systemic_path/cardio/decidualvasculopathy.html Decidual vasculopathy (brown.edu)]. | |||
==Sign out== | |||
<pre> | |||
PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAREAN SECTION: | |||
- DECIDUAL VASCULOPATHY. | |||
- PLACENTA SMALL FOR GESTATIONAL AGE (222 GRAMS). | |||
- PLACENTAL DISC WITH EARLY THIRD TRIMESTER VILLI WITH: | |||
-- MULTIPLE PLACENTAL INFARCTS. | |||
-- PERIVILLOUS FIBRIN DEPOSITION. | |||
- THREE VESSEL UMBILICAL CORD WITHIN NORMAL LIMITS. | |||
- FETAL MEMBRANES WITHIN NORMAL LIMITS. | |||
COMMENT: | |||
The 10th percentile placental mass (pre-fixation) for 32 weeks and 6 | |||
days is approximately 247 grams. | |||
</pre> | |||
===Suggestive of decidual vasculopathy=== | |||
<pre> | |||
PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAREAN SECTION: | |||
- CHANGES SUGGESTIVE OF DECIDUAL VASCULOPATHY (DECIDUAL VASCULITIS). | |||
- PLACENTAL DISC WITH EARLY THIRD TRIMESTER VILLI AND A PLACENTAL INFARCT | |||
(2.5 CM IN MAXIMAL DIMENSION). | |||
- THREE VESSEL UMBILICAL CORD WITHIN NORMAL LIMITS. | |||
- FETAL MEMBRANES WITHIN NORMAL LIMITS. | |||
</pre> | |||
==See also== | |||
*[[Placenta]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Placenta]] | |||