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Difference between revisions of "Angiomyolipoma"
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(→Microscopic: +leiomyoma) |
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| Micro = smooth muscle, adipose tissue (not always present), abundant blood vessels | | Micro = smooth muscle, adipose tissue (not always present), abundant blood vessels | ||
| Subtypes = conventional, epithelioid angiomyolipoma | | Subtypes = conventional, epithelioid angiomyolipoma | ||
| LMDDx = [[clear cell renal cell carcinoma]] (esp. for epithelioid variant), [[Xp11.2 translocation carcinoma]] (esp. for epithelioid variant), well-differentiated retroperitoneal [[sarcoma]] (esp. [[leiomyosarcoma]] & [[liposarcoma]]), [[renal cell carcinoma with sarcomatoid differentiation]] | | LMDDx = [[clear cell renal cell carcinoma]] (esp. for epithelioid variant), [[Xp11.2 translocation carcinoma]] (esp. for epithelioid variant), well-differentiated retroperitoneal [[sarcoma]] (esp. [[leiomyosarcoma]] & [[liposarcoma]]), [[renal cell carcinoma with sarcomatoid differentiation]], [[renal leiomyoma]] | ||
| Stains = | | Stains = | ||
| IHC = HMB-45 +ve, Melan A +ve, SMA +ve, PAX8 -ve, CK (pooled) -ve | | IHC = HMB-45 +ve, Melan A +ve, SMA +ve, PAX8 -ve, CK (pooled) -ve | ||
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**[[Leiomyosarcoma]]. | **[[Leiomyosarcoma]]. | ||
*[[Renal cell carcinoma with sarcomatoid differentiation]]. | *[[Renal cell carcinoma with sarcomatoid differentiation]]. | ||
*[[Renal leiomyoma]] - desmin +ve, HMB-45 -ve.<ref name=pmid25517956>{{Cite journal | last1 = Patil | first1 = PA. | last2 = McKenney | first2 = JK. | last3 = Trpkov | first3 = K. | last4 = Hes | first4 = O. | last5 = Montironi | first5 = R. | last6 = Scarpelli | first6 = M. | last7 = Nesi | first7 = G. | last8 = Aron | first8 = M. | last9 = Sangoi | first9 = AR. | title = Renal Leiomyoma: A Contemporary Multi-institution Study of an Infrequent and Frequently Misclassified Neoplasm. | journal = Am J Surg Pathol | volume = | issue = | pages = | month = Dec | year = 2014 | doi = 10.1097/PAS.0000000000000354 | PMID = 25517956 }}</ref> | *[[Renal leiomyoma]] - very rare - desmin +ve, HMB-45 -ve.<ref name=pmid25517956>{{Cite journal | last1 = Patil | first1 = PA. | last2 = McKenney | first2 = JK. | last3 = Trpkov | first3 = K. | last4 = Hes | first4 = O. | last5 = Montironi | first5 = R. | last6 = Scarpelli | first6 = M. | last7 = Nesi | first7 = G. | last8 = Aron | first8 = M. | last9 = Sangoi | first9 = AR. | title = Renal Leiomyoma: A Contemporary Multi-institution Study of an Infrequent and Frequently Misclassified Neoplasm. | journal = Am J Surg Pathol | volume = | issue = | pages = | month = Dec | year = 2014 | doi = 10.1097/PAS.0000000000000354 | PMID = 25517956 }}</ref> | ||
===Images=== | ===Images=== | ||